Identical 14-year-old twins, Nicole and Jonas Maines, started out life as brothers Wyatt and Jonas. Nicole is transgender.

Jonas and Wyatt during their second birthday party.

When he was 4, Wyatt asked his mother: "When do I get to be a girl?" In the fifth grade, Wyatt's name was legally changed to Nicole.

Wyatt often liked to dress in girl's clothes and identified more as a girl than a boy.

Jonas, Nicole and their parents, Kelly and Wayne Maines.

Jonas and Wyatt playing when they were 2.

Nicole is part of the groundbreaking clinic at Children's Hospital founded by Dr. Norman Spack, that helps families deal with emotional and medical issues that arise from having a transgender child. The Maines are the first identical twins the program has seen.

Wyatt posed with barbie dolls at age 4.

A self-portrait Wyatt Maines drew in first grade. Throughout elementary school, Wyatt told classmates he was a "girl-boy."

Jonas and Wyatt Maines at age 9. Wyatt started growing his hair longer and started talking about a name change in fourth grade.

During the interview, Nicole checks on her brother, who had become quiet and withdrawn and whispers words of encouragement in his ear.

An essay by Wyatt Maines, written in the fourth grade.

Jonas and Nicole play video games in Jonas's room.

Drawing and poem by Wyatt Maines, age 7. In the fifth grade, Nicole was harassed and bullied and the family eventually decided to change schools.

Jonas lifts his sister, Nicole, as they horse around in her bedroom. Both have black belts in tae kwon do.

Self-portrait by Wyatt Maines, fourth grade.

In Nicole's room. Jonas makes Nicole's bed to neaten up for a photo shoot. Nicole has been taking male hormone suppressors since she was 11; the next step is to add female hormones.

"I love having a sister," says Jonas. "We have a very strong relationship."