It is perhaps the most famous art pilgrimage in Europe — an itinerary that for quivering aesthetes can crystallize a life’s purpose and meaning in the same way a pilgrimage to Mecca can for Muslims.

I’m talking, of course, about the Piero della Francesca trail. This tour of the great Renaissance artist’s best-known works in Tuscany takes in the towns of Arezzo, Sansepolcro (the artist’s birthplace), Anghiari, Monterchi, and Urbino.