Vertex pledges $500 million for charitable efforts over 10 years

One area of focus for the pharmaceutical firm will be workforce training.

Amazon employees arrived at work in Seattle one morning, passing an Amazon Go store, a beta store testing a cashierless grocery store model.

One home, under Amazon

From the living room to the office, the e-commerce giant works to make its goods and services essential to customers’ lives.  

STAT

Genetics booms, but doctors lack interest

Therapies are in the works to treat a number of rare, inherited disorders, from blindness to nerve disease. But there’s a shortage of doctors trained to diagnose and treat such illnesses.

Ruth O’Brien, 85, recently received the second annual Pioneering Relauncher Award.

BOLD TYPES

Ruth O’Brien, a lawyer in the ’50s, gets a career award (and son Conan cracks some jokes)

O’Brien was recently recognized by the Boston career reentry company iRelaunch with the second annual Pioneering Relauncher Award.

Latest Business headlines

Bombardier-Airbus deal on airliner could help avert massive US tariffs

Airbus will hold a 50.1 percent stake in the CSeries venture, and some production could be moved to Alabama.

Facebook is said to seek staff with US security clearance

The company thinks the measure is necessary to prevent foreign powers from manipulating future elections through its social network.

Nearly every modern, protected Wi-Fi network is vulnerable, says government cyber watchdog

Users are being warned to update their devices to protect against a newly discovered vulnerability.

Supreme Court agrees to take on US-Microsoft dispute over e-mails

The justices intervened in a case of a federal drug trafficking investigation that sought e-mails that Microsoft keeps on a server in Ireland.

Weinstein Co. agrees to a rescue investment from Colony Capital

The embattled studio is reeling from the scandal surrounding co-founder Harvey Weinstein.

Newsletters

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An afternoon recap of the day’s most important business news, delivered Monday through Friday.

The Fine Print

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Sean P. Murphy is the Globe’s consumer columnist, and he’s here to take your queries.

Globe Magazine

Special section | Game Changers

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2017/05/11/BostonGlobe.com/Business/Images/gamechangershoriz-6383.jpg 51 bright ideas and breakthroughs for 2017

In a revolutionary place like Boston, innovators and innovations are as common as bad drivers. See who made our annual list.

More Business headlines

GrubHub, which was listed on the New York Stock Exchange in 2014, has completed its purchase of Foodler.

Goodbye, Foodler: The take-out delivery service is shutting down

Competitor GrubHub has completed its takeover of Boston-based Foodler.

Stock indexes post slight gains, extending winning streak

US stocks posted modest gains Monday, extending a record-setting run into a sixth straight week.

White men rule business but many feel left out at work, survey shows

More than a third of Americans in a survey said the heightened focus on diversity at work has overlooked white men, according to Ernst & Young.

Tuesday’s business agenda

Info session on success in business, networking opportunity for women in business, and other notable events and things to know.

A view of 1 Washington Park and the Audible building seen from the Broad Street train station in Newark.

Newark says, hey Amazon, look over here

The city sits astride an extensive transportation network of trains, planes, and automobiles. It has six colleges and universities with a total of 60,000 students.

GE CEO John Flannery has said he’ll consider all options to regain investor confidence.

How much does GE earn? It’s hard to tell, investors say

Last quarter, General Electric Co. reported earnings of 28 cents a share. Also 13 cents a share, 19 cents a share and 15 cents a share — all at the same time.

This Sunday, Oct. 15, 2017 image made from video shows a crying passenger at an airport in Perth, Australia after an Indonesia AirAsia flight from Australia to the holiday island of Bali returned safely to the airport. Passengers on the flight described a panicked flight crew announcing an emergency and oxygen masks dropping from the ceiling after their airliner lost cabin air pressure and rapidly descended. (Channel 7 via AP)

Passengers accuse AirAsia crew of setting off panic during plane’s rapid descent

Oxygen masks dropped from the ceiling as the plane rapidly descended tens of thousands of feet in what is being investigated as a potential depressurization.

Justices to hear government’s e-mail dispute with Microsoft

At the heart of the issue is whether e-mails stored on a Microsoft server in Ireland were beyond the reach of a search warrant.

“We’re very excited,’’ said Laurence Reid, chief executive of Warp Drive. “There’s an ongoing and growing global crisis in treating drug-resistant pathogens all over the world.”

Cambridge biotech signs deal to take on ‘superbugs’

Warp Drive Bio will get as much as $87 million up front from drug giant Roche.

Federal Reserve chairman Janet Yellen was upbeat Sunday when discussing the state of the US economy.

Economy still in good health, says Fed’s Janet Yellen

Yellen made the comments Sunday during a meeting of the Group of 30 in Washington.

Jim Jehle, 66, a senior project manager, meets monthly with his younger mentor at Sachse Construction in Detroit. Some companies call it reverse mentoring.

Millennials drag their bosses into the 21st century

Junior workers once had a fairly predictable set of tasks. Now, many young professionals have a new mandate.

Nick Leschly, the CEO of Bluebird Bio, which is developing gene therapies for rare diseases.

STAT

The potential of gene therapy is breathtaking. So is the price tag.

A FDA panel’s recommendation clears the way for the approval of a breakthrough treatment, but will desperate patients be able to get it?

STAT

Hospitals get creative in hiring nurses amid a national shortage

Hospital administrators are making even more enticing offers — five-figure signing bonuses, free degrees, loan forgiveness — than before.

shirley leung

Whether Amazon comes to Boston or not, we should still make Boston better

Sure, Jeff Bezos is the visionary we want, but let’s not forget the vision we have for ourselves.

Raynham, MA -- 10/12/17 -- Farmers Marie Kaziunas (left), and Chuck Currie, pose for a portrait with their chickens, at Freedom Food Farm, on October 12, 2017, in Raychem, Massachusetts. (Kayana Szymczak for The Boston Globe)

sean p. murphy | the fine print

An accident at a farmers’ market, and then a frustrating battle for restitution

As he loaded his truck early one Saturday morning last May, farmer Chuck Currie had high hopes of raising some badly needed cash by selling fresh veggies and pasture-raised beef.

JOB DOC

Is leaving a nonprofit for a corporate job considered selling out?

If you left a nonprofit because you recognized that the lifestyle it created for you wasn’t something you wanted, there’s no spin needed.

Boston, MA - 8/22/2017 - Sisters Cruz Sanchez (cq), left, of Mattapan, and Frances Rosado (cq), of Dorchester, shop. Tropical Foods, in Roxbury, caters to an international community. Customers are asked about a possible food delivery service in the area. Photo by Pat Greenhouse/Globe Staff Topic: tropicalfoods Reporter: Lauren Feiner

Food stamps, quality concerns may keep low-income shoppers offline

Stores offering fresh international produce are popular with immigrants, especially those depending on government benefits, who are still unable to use them to buy groceries online.

MICHELLE SINGLETARY | THE COLOR OF MONEY

Learn how to protect seniors from fraud

More than two-thirds of caretakers reported that a scammer had targeted their elderly relatives, according to a new survey.

The Bayside Expo Center was bought by UMass Boston in 2010.

Developers want chance to build on Bayside Expo site

UMass Boston said it received 16 letters of interest regarding the 20-acre Dorchester plot that it bought for $18.7 million in 2010.

Fidelity’s Gavin Baker posed for a portrait in 2014.

Abby Johnson sends clear message with fund manager’s firing

The way Gavin Baker’s departure played out was highly unusual in a world where one manager can bring in millions of dollars in fees each year with a successful fund.

German chemicals and pharmaceuticals giant Bayer announced a multi-billion euro deal Friday to sell parts of its agrichemical business to rival BASF, easing the path of its planned takeover of US seed maker Monsanto.

BASF to buy Bayer units for $7 billion

The deal would pave the way for Bayer’s anticipated merger with US rival Monsanto.

Michael Bloomberg and Abigail Johnson onstage at Friday’s HUBweek event.

In a rare public conversation, Johnson and Bloomberg talk innovation, housing costs, and Trump

Fidelity Investments chief executive Abigail Johnson and former New York mayor Michael Bloomberg appeared at a HUBweek event on City Hall plaza.

Governor Charlie Baker.

Baker assails move to halt Obamacare subsidies; Healey joins suit to protect payments

Governor Charlie Baker joined Democrats in denouncing the White House move to roll back a key component of the Affordable Care Act.

Dear Jeff Bezos: Come and help us build a better Boston together

Join the discussion on Boston’s potential as Amazon’s second headquarters.

Coastal bird biologist Carolyn Mostello says the rarest bird she has seen is the yellow-nosed albatross.

ON THE JOB

For this ‘Bird Lady,’ there’s nothing quite like seeing a yellow-nosed albatross

“I think all people who study birds are called either ‘Bird Lady’ or ‘Bird Guy’ because it’s easier than remembering our real names,” says Mass. biologist Carolyn Mostello.

Watch live: Michael Bloomberg sits down with Abigail Johnson

The head of Fidelity is speaking with the former mayor of New York City as part of HUBweek.

President Trump signed an executive order on health care at the White House Thursday.

Evan Horowitz | Quick Study

Why Trump’s move to kill Obamacare insurance subsidies might not matter much

In the Byzantine world of health care, the effect on lower-income Americans could be limited.

A battery of pipettes on a robot used for DNA gene sequencing in a lab.

CONSUMER ALERT

Proceed with caution before buying a home DNA test

It sounds straightforward, but these tests may have unexpected financial, and physical, consequences.

Former MBTA chief administrator Brian Shortsleeve.

Former MBTA chief Shortsleeve raises $180m for venture capital fund

His M33 Growth fund will invest in young, fast-growing companies.

Edmit’s current employees are Sabrina Manville, Nick Ducoff, and Christopher Jelly.

SCOTT KIRSNER | INNOVATION ECONOMY

They’re out to reveal the ‘dirty little secret of higher education’

These Boston startup founders say there are tuition discounts at many colleges — you just have to know how to find them.

FILE - In this Nov. 22, 2015 file photo, Roy Price attends the world premiere of

Amazon Studios chief on leave following harassment claims

Studio executive Roy Price is on a leave of absence effective immediately, Amazon said in a statement.

Alphabet Inc. executive chairman Eric Schmidt spoke at the Inclusive Innovation Challenge Celebration, part of HUBweek.

Alphabet Inc.’s Schmidt touches on AI, ethics, and Trump in HUBweek discussion

“The current administration’s policies are going in the wrong direction,” Eric Schmidt said. “And I’m not sure how to fix that.”

Opening-day customers at the Trader’s Joes in Allston got leis to wear;

Builders offer a new perk: a very short walk to the grocery store

Builders looking to fill their ground floors with businesses that double as amenities are teaming up with grocers who want easy access to upscale clientele.

The Fidelity OTC Portfolio, which Gavin Baker took over in July 2009, has returned 33.4 percent this year, compared with 23.5 percent for the Nasdaq Composite index, according to Bloomberg data.

Fidelity said to fire star fund manager after sexual harassment allegation

The decision to dismiss Gavin Baker was made by CEO Abigail Johnson after a female employee filed a complaint with HR.

Facebook COO Sheryl Sandberg said ads linked to Russia trying to influence the US presidential election should be released.

Sandberg says Facebook will hand over more data on Russia-linked ads

Sheryl Sandberg, Facebook’s chief operating officer, said Thursday that the company had promised to provide more information, including ad-targeting data, to government officials as part of a federal investigation into Russian meddling in the 2016 election.

Divorce bill deadlock: EU laments progress on Brexit

Brexit talks have hit a deadlock on the key issue of Britain’s exit bill in the divorce, the European Union’s chief negotiator said Thursday, adding that the slow-moving talks won’t be broadened anytime soon to include future trade relations.

Friday’s business agenda

Etiquette bootcamp, night club in tech, and other notable events and things to know.

Media and retail losses pull stock indexes away from records

U.S. stock indexes retreated from their record highs Thursday as retailers and media companies declined and investors shrugged at quarterly reports from a few big banks.

CarGurus revved up on first day of trading

The comparison-site for car shopping saw its shares soar after a $150 million IPO.

XL Hybrids tanks up on new funding

A $22 million venture round will fuel expansion, hiring for company that converts vehicles to hybrids.

Amazon’s donation to the St. Mary’s Center comes as the city is preparing a bid for the e-retailer’s so-called second headquarters.

Amazon donating $1 million to Dorchester nonprofit

St. Mary’s Center provides housing and job training to homeless families.

Tech Lab by Hiawatha Bray

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Bray writes about technology for the Business section. His Tech Lab column appears on Thursdays.

Shirley Leung

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Leung writes a business column every Wednesday and Friday. Previously she served six years as the business editor overseeing daily and Sunday coverage.