General Catalyst hires its first female managing director

Holly Maloney McConnell, who was named one of Forbes’ “30 Under 30” in 2015, will join the firm’s Boston office after seven years as a principal at Waltham’s North Bridge Growth Equity.

A ground crew member enters an Air Force C-5M Super Galaxy prior to a training flight at Westover Air Reserve Base in Chicopee.

Westover’s oldest planes fall quiet after nearly 50 years

The residents of Chicopee may not miss the trademark screech of the C-5A Galaxy military jet, the last of which left Westover Air Reserve Base this month.

“It’s outgrowing our wildest expectations,” LabCentral’s cofounder, Johannes Fruehauf, said of the incubator’s success.

Just months after expanding, LabCentral growing again

A Cambridge lab-sharing space is adding another 33,000 square feet to meet demand from startups — and it isn’t the lab’s first expansion.

Boylston Street customers in Boston waited to purchase the iPhone 7 last fall.

TECH LAB

Should you line up for the new iPhone 8? Or wait for the iPhone X?

The iPhone 8 goes on sale Friday, iPhone X in November. Which is worth the wait?

Latest Business headlines

Gubernatorial candidate Warren: Worcester is the best place for Amazon

The Newton mayor says a headquarters in central Mass. city would help lessen state’s economic inequality.

Uber to lose its license to operate in London

London’s transport authority said Uber was not “fit and proper to hold a private hire operator license.”

STAT

Making sense of Alnylam’s one-day gain of $3.5 billion

At $113 per share, Alnylam is worth $10.7 billion. The stock added $3.5 billion in market value on Wednesday alone.

STAT

CVS tightens restrictions on opioid prescriptions in bid to stanch epidemic

CVS Caremark, which has 90 million plan members, the company will introduce three new policies, effective in February.

Friday’s business agenda

A toast to Boston’ s first startup week, US Navy hackathon, and other notable events and things to know.

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Sean P. Murphy is the Globe’s consumer columnist, and he’s here to take your queries.

Globe Magazine

Special section | Game Changers

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2017/05/11/BostonGlobe.com/Business/Images/gamechangershoriz-6383.jpg 51 bright ideas and breakthroughs for 2017

In a revolutionary place like Boston, innovators and innovations are as common as bad drivers. See who made our annual list.

More Business headlines

Diebold Nixdorf employees Stephen Cheek and Lashanda Mitchell checked out ATMs at the firm’s factory.

ATM at 50: An oddity then, but it changed consumer behavior

ATMs, known for spitting out $20 bills (and imposing fees if you pick the wrong one), turn 50 years old this year.

US stocks slip for the first time this week

A slide in technology companies weighed on stocks Thursday, pulling the market lower for the first time this week.

A woman holding an umbrella walked past a construction site in Beijing. Standard & Poor's slashed China's credit rating on Thursday, warning that a prolonged period of debt growth had raised

S&P downgrades China’s debt, citing a surge in lending

China and the world received a fresh warning Thursday that the country’s dramatic debt binge of recent years threatens the stability of one of the global economy’s most important growth engines.

Freshness dates on food products can be more confusing than helpful.

CONSUMER ALERT

Will a ‘use by’ date keep us from throwing out perfectly good food?

Changes are coming to the way manufacturers determine freshness.

Someone made a fake Equifax site. Then Equifax linked to it three times

People create fake versions of big companies’ websites all the time, usually for phishing purposes. But the companies do not usually link to them by mistake.

Abbie Celniker, chair of the board of MassBio, said the group wanted to delve deeper into gender inequality.

Shirley Leung

Why too few women in life sciences is bad for business

A new report provides a road map of the barriers women face throughout their careers, and explains how a diverse workforce is good for the bottom line.

BOSTON Ñ 2/13/2015: Nick Rellas, co-founder of Drizly, talks with Phuc Truong, the Senior Vice President of Ad Sales, on Friday, Feb. 13, at the Drizly office on Boylston Street in downtown Boston. Drizly is a phone App that allows for delivery of beers, wines and liquors to customers, and was founded by Rellas and Justin Robinson in 2012, after graduating from Boston College.. (Sean Proctor/Globe Staff)

Amazon could find those 50,000 jobs hard to fill in Boston area

Tech companies say they already have problems finding qualified candidates, but others believe Amazon could establish Boston as a tech mecca.

Employee representatives hold half of ThyssenKrupp’s supervisory board seats, and may resist any job cuts or plant shutdowns.

Tata Steel and ThyssenKrupp agree to create European steel giant

The steelmakers hope the combined company will be better equipped to tackle chronic problems like an excess of capacity in the industry.

Financial plumber State Street embraces artificial intelligence

State Street Corp., founded in 1792, and artificial intelligence haven’t often been mentioned in the same sentence -- until now.

Target Corp. will add 100,000 seasonal positions for the holidays, 40 percent more than in 2016.

Holiday sales projected to jump as consumer jitters subside

Consumers appear to be more comfortable opening their wallets than in the aftermath of 2016’s tumultuous presidential election.

State panel backs switching to all-year daylight saving time

One man’s quest to put Massachusetts on daylight saving time all year was endorsed on Wednesday by a state commission.

Pfizer sues Johnson & Johnson, alleging anticompetitive practices to maintain a drug monopoly

A legal brawl between two of the world’s largest drug companies could shape the future of a nascent market of copycat drugs.

Stocks wobble after Fed announcement but close higher

Modest gains again nudged both the Dow and S&P 500 to record highs.

Alnylam’s drug would be the first based on RNA interference.

Alnylam’s rare-disease drug shines in trial; stock soars 51 percent

Alnylam Pharmaceuticals announced positive results from a closely watched trial of patisiran, the Cambridge biotech’s treatment for a rare nerve disorder, FAP.

The Communications Decency Act shields Internet site operators from liability for the awful things their users post. But a Senate committee on Tuesday held hearings on changing the law.

TECH LAB

Banning sex-slave ads shouldn’t trigger a fight

The Communications Decency Act shields Internet operators from liability for the awful things their users post. But Congress is ready to change the law.

Federal Reserve Chair Janet Yellen speaks during a news conference following the Federal Open Market Committee meeting in Washington on Wednesday.

Fed outlines a start to gradually unwinding its post-crisis stimulus

The Federal Reserve will begin shrinking its enormous portfolio of bonds, amassed after the 2008 financial crisis. That could mean higher rates on loans over time.

Thursday’s business agenda

Mortgage rates, business meet and greet, startup success panel, and other notable events and things to know.

FILE - This Sept. 6, 2012, file photo shows the Amazon logo in Santa Monica, Calif. Kohl's, which is opening some in-store Amazon shops, will start accepting returns for the online retailer at some of its stores in Los Angeles and Chicago starting in October 2017. (AP Photo/Reed Saxon, File)

Received an Amazon e-mail about a baby registry you don’t have? You’re not alone

Those who got the e-mail — and decided to talk about it on Twitter — reacted with a mix of amusement, fear, and anger.

Boston Mayor Martin J. Walsh is calling for an expansion of public park space — like the Harborwalk — along the city’s waterfront.

Park plan envisions fun — and flood control — along Fort Point

Mayor Martin Walsh unveiled plans for a “landmark” network of parks along the channel, connected by pedestrian bridges, marshlands, and islands.

Cambridge, MA - 5/3/2016 - John Maraganore, CEO of Alnylam Pharmaceuticals, pose for a portrait in his office in Cambridge, MA, May 3, 2016. (Keith Bedford/Globe Staff)

Alnylam’s rare disease drug shines in trial, paving way for a brand-new class of medicines

Alnylam Pharmaceuticals announced positive results Wednesday from a closely watched trial of a drug designed to treat a rare nerve disorder.

Mayor Walsh: We will hold climate summit here after all

Mayor Martin J. Walsh has decided to hold a climate summit in Boston after all despite reluctance on the part of the Trump administration to pull one together this year.

13seaport - A rendering of a two-story retail building between Seaport Blvd. and Northern Ave., with a newly-proposed rooftop garden that would be open to the public at Seaport Square in Boston. (WS Development)

Lawmaker wants a library branch in the Seaport

WS Development, owner of the 12.5-acre site, last week proposed adding three theaters.

The Rev. Martin Luther King Jr. greeted a supporters in April 1965 during a match to on Boston Common. A memorial to the civil rights icon, who attended Boston University, could be placed on the Common or elsewhere in the city.

Mayor backs new plan to build MLK memorial in Boston

A Boston CEO is working to raise more than $5 million to pull off what politicians have been unable to do.

Stocks’ slight gains again break records

Wall Street capped a day of mostly listless trading Tuesday with a slight gain.

Feng Zhang posed for a portrait at the Broad Institute in October 2015.

STAT

$500,000 Lemelson-MIT Prize goes to a bioengineer

Feng Zhang is a key developer of CRISPR genome-editing technology.

Toys R Us joins bankruptcy list as Amazon exerts influence

Analysts say the toy chain needs to improve its online services and offering special experiences in the stores.

Boston, MA -- 9/19/2017 - A man takes a picture of Steve Tolman, President MA AFL-CIO as he speaks during a press conference held to support slowly increasing the state's minimum wage to $15/hour. (Jessica Rinaldi/Globe Staff) Topic: 20minimumwagepic Reporter:

Supporters of higher minimum wage urge lawmakers to enact hike

Bills in the House and Senate would increase Massachusetts’ minimum wage by $1 a year over the course of four years.

Agenda

Startup panels, networking, and other notable things to know.

The Benny's store in Plymouth, along with the rest of the 31-store chain, is closing.

4,500 signatures (and counting) in support of Amazon buying Benny’s

Fans of the iconic New England chain see a possible savior in Amazon — the very company that Benny’s is losing out to.

Harvard has been struggling to right its $37.1 billion endowment.

Harvard’s endowment posts 8.1 percent return, lagging behind peers

The university’s endowment, which funds 36 percent of the university’s operations, continues to face problems, the latest results show.

The key senators behind this last-ditch effort to repeal Obamacare are Lindsay Graham (right) and Bill Cassidy.

Evan Horowitz | Quick Study

The GOP’s latest Obamacare repeal bill could devastate Mass.

The Cassidy-Graham proposal would sharply reduce the funding Massachusetts uses for Medicaid.

Employees worked in Threat Stack’s Boston offices in September 2016.

Threat Stack boosts funding with $45 million round

Cyber security firm backed by Fidelity affiliate.

Cambridge biotech Disarm raises $30m for drug to slow ALS, other degenerative diseases

The treatment would work to slow or halt the progression of degenerative diseases that affect the nervous system, from ALS to glaucoma.

Toys R Us Inc. filed for Chapter 11 bankruptcy on Monday.

Toys R Us joins bankruptcy list as Amazon exerts influence

Analysts say the toy chain needs to improve its online services and offer special experiences in the stores.

Brent Saunders sees a deal with the Mohawk tribe as in line with his “social contract.”

STAT | PHARMALOT

This CEO promised fair drug pricing, but his latest move is raising anger (and eyebrows)

Allergan’s Brent Saunders made a creative deal to protect patents on a lucrative drug. It’s calling into question his `social contract’ with consumers.

Image of a planned Brothers Market by Roche Bros. in Waltham.

Waltham is getting a (smaller) Roche Bros.

The Wellesley chain is planning a scaled-down version of its regular supermarkets.

CEO Katie Rae sees a recognition that the venture capital world must find better ways to evaluate new technologies.

MIT’s new investing Engine raises $200 million

The program, launched in 2016, provides startup founders with money, technical expertise, and access to specialized equipment.

Former Fox News contributor Scottie Nell Hughes claims in a lawsuit that she was raped by longtime anchor Charles Payne. Above, the Fox News studios building in Manhattan.

Former Fox News contributor says rape allegation blacklisted her

Scottie Nell Hughes claims she was raped by Fox Business Channel anchor Charles Payne.

Two people familiar with the case say the Google Shopping site is being offered in a bid to appease European Union regulators.

Google said to offer shopping space to rivals

It’s a bid to appease European Union regulators and avoid further antitrust fines, according to two people with knowledge of the case.

The Toys “R” Us store in New York’s Times Square in 2015.

Toys ‘R’ Us is said to file for bankruptcy as soon as today

The Chapter 11 reorganization of America’s largest toy chain would deal another blow to brick-and-mortar retail.

Equifax Inc. learned about a major breach of its computer systems in March — almost five months before the date it has publicly disclosed, according to three people familiar with the situation.

Equifax executives’ stock sales said to be focus of criminal probe

Equifax learned about a major breach of its systems in March — five months before the date it has publicly disclosed, according to three people.

Tech Lab by Hiawatha Bray

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Bray writes about technology for the Business section. His Tech Lab column appears on Thursdays.

Shirley Leung

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Leung writes a business column every Wednesday and Friday. Previously she served six years as the business editor overseeing daily and Sunday coverage.