Plus-size ambitions for James Rhee and the Ashley Stewart brand

What does a Korean-American father of three have to do with a fashion label that’s popular with black women? Everything.

epa05514939 (FILE) A file picture dated 27 January 2015 of the company's logo at an Apple Store in Washington, DC, USA. Reports state that the results of European Commission investigations examining whether decisions by tax authorities in Ireland, with regard to the corporate income tax to be paid by Apple comply with the EU rules on state aid, are due to be announced on 30 August 2016. The Commission has been investigating under EU state aid rules certain tax practices in several Member States following media reports alleging that some companies have received significant tax reductions by way of 'tax rulings' issued by national tax authorities. EPA/SHAWN THEW *** Local Caption *** 52554029

Apple gets hit with $14.5b tax bill

Ireland gave billions in euros worth of illegal tax benefits to the US technology giant, the European Union ruled.

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As Parkinson’s patients wait, Fox Foundation and scientist feud over drug trial

As a result, a crucial clinical trial of the most promising treatment for Parkinson’s disease in decades might be delayed.

When the sale closes, the combined company, Dell Technologies Inc., will keep its enterprise computing division in EMC’s hometown of Hopkinton.

EMC sale clears last hurdle, Dell to close on purchase next week

The $65 billion tech takeover, the biggest in that industry’s history, has won approval of Chinese regulators.

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FDA to examine off-label drug issue

The agency has planned November hearings on what doctors can be told about off-label uses.

Mattel’s American Girl dolls to be sold at Toys R Us stores

Making the dolls available in more places could help Mattel Inc. reverse the brand’s declining sales.

Bold Types

Will his bid take off at Logan?

Two decades ago New England Development unsuccessfully bid on the rights to oversee Logan’s commercial real estate. Airmall and Westfield won instead. Bow now the Massachusetts Port Authority is putting the business out to bid again.

Sunovion to buy Cynapsus for $620 million

Marlborough biotech Sunovion Pharmaceuticals Inc. said Thursday it will pay $624 million to acquire Toronto-based Cynapsus Therapeutics Inc.

From Cadillac, an almost-self-driving car

In highway driving, the CT6’s semi-automatic features can manage nearly all the work.

Sponsored by Rockland Trust

Loyalty keeps Sullivan Tire’s wheels in motion

Since 1955, family-owned Sullivan Tire has treated customers like it treats family members—with loyalty and respect. Seven decades of growth later, it’s still working.

This content was produced by Boston Globe Media in collaboration with the advertiser. The news and editorial departments of The Boston Globe had no role in its production or display.

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Threats characterize Alere-Abbot Labs falling out

The unraveling of a $5.8 billion deal to buy Waltham diagnostic company Alere Inc. was laid out in stunning detail in a lawsuit Wednesday.

Thursday’s business agenda

Mortgage rates, networking, and more notable events and things to know.

EnerNOC gets ConEd contract for Brooklyn, Queens

The Boston company will help the utility reduce electricity demand in the boroughs, potentially delaying construction of a huge new substation.

This undated photo provided by Biogen shows new signage in front of one of the biotechnology company's buildings in Cambridge, Mass. Biogen Idec Inc. is shortening its name to just Biogen as of Monday, March 23, 2015. (AP Photo/Biogen) kendallsquare100

Biogen data support Alzheimer’s research

Findings backed up Biogen’s earlier report showing an experimental compound slowed mental decline in patients with Alzheimer’s disease.

Too low for too long could be risky, Rosengren warns

Warning that keeping interest rates too low for too long is risky, Eric Rosengren, the president of the Federal Reserve Bank of Boston joined a growing cadre of central bankers suggesting that another rate increase is fast approaching.

“Health care is sucking up all of the money,” said Joshua Archambault, senior fellow at Pioneer Institute.

Health care law to cost Mass. $162m over 10 years, report says

The costs come in the form of a fee that is part of the Affordable Care Act, a free-market-oriented think tank says.

Waze sets a variable fee of up to 54 cents per mile to reimburse drivers for gas and maintenance, with riders paying the fee.

Google to expand Waze carpooling service in San Francisco

The move could set up a showdown with Google’s one-time ally, Uber.

Novartis has developed a biosimilar version of Amgen’s anti-inflammatory drug Enbrel.

Novartis wins federal OK for biosimilar version of Amgen’s Enbrel

Amgen’s blockbuster anti-inflammatory drug is among the top-selling drugs in the world.

LA paying $200m to settle lawsuit over disabled housing

Los Angeles agreed Tuesday to spend at least $200 million over a decade to provide thousands of apartments for people with disabilities.

Uber chief executive Travis Kalanick wrote in a company blog post that “our rapidly growing marketing efforts needed to be far more integrated with our city operations.”

Uber hires Target marketing chief to oversee operations

By hiring Jeff Jones, Uber has enlisted a retail industry veteran to oversee the ride-hailing giant’s main business.

Apple owes $14.5 billion in back taxes to Ireland, E.U. says

The record penalty is expected to worsened tensions with the United States over the bloc’s crackdown on sweetheart deals with global multinationals.

Wednesday’s business agenda

Workshops, networking, and more notable events and things to know.

FILE - In this Wednesday, Dec. 7, 2011 file photo, a person stands near the Apple logo at the company's store in Grand Central Terminal, in New York. Apple will have to pay up to 13 billion euros ($14.5 billion) plus interest in back taxes to Ireland after the European Union found Tuesday aug. 30, 2016 that the U.S. technology giant had paid next to no tax at all across the bloc's 28 countries for over 11 years. The ruling is a dramatic escalation by the EU executive Commission in its battle to have multinationals pay their fair share in the region. (AP Photo/Mark Lennihan, File)

Apple said to prepare upgrades for iPhone, new features for iPad

Apple is holding an event on Sept. 7, and the keynote will focus on upgraded versions of the iPhone, among other features.

FILE- In this Aug. 12, 2008 file photo, shoppers walk in front of a Abercrombie & Fitch store in San Jose, Calif. Sales fell more than expected in September and October as fewer people headed to the mall and shoppers shunned clothing with the retailer’s logo on it. It also reported weaker sales at its European stores, especially at its Hollister brand. Abercrombie’s stock fell as much as 14 percent Friday, Nov. 7, 2014, reaching a two-year low. (AP Photo/Paul Sakuma, file)

Abercrombie & Fitch can’t get the grown-ups into the kids’ clothes

Abercrombie & Fitch wants adults in their twenties to wear its clothes. The grown-ups appear to be saying: Why would I?

Map of planned new ski trails at Waterville Valley Resort in New Hampshire. Construction on the new slope, dubbed

Waterville Valley Resort to build new ski trails

Construction has begun on a new slope dubbed “Green Peak,” which is set to open this winter.

Apple Operations International, a subsidiary of Apple Inc, is seen in Hollyhill, Cork, in the south of Ireland August 30, 2016. REUTERS/Stringer

Why Ireland doesn’t want to take billions from Apple

The Irish government joined Apple in vowing to appeal the European Commission’s judgment that the company didn’t pay the correct volume of tax.

Instacart sends people into stores like Whole Foods to fulfill grocery delivery orders. Fulfilled orders are stored until delivery.

Instacart expands high-tech grocery delivery, with hopes of helping grandma

For its next act, the company wants to help aging residents navigate the necessities of hometown living.

Boston-based General Electric Co. is donating $7.5 million for the MIT Energy Initiative’s research efforts.

GE joins MIT energy initiative, donates $7.5 million

The money will help pay for the initiative’s work on solar power, the electric grid, industrial batteries, and carbon sequestration.

The drug industry has spent $171 million on unbranded ads so far this year.

STAT

Drug companies spending more on unbranded ads

The stealthy and lightly regulated form of drug marketing focuses on educating the public about a condition — which the pharma company just happens to sell a product to treat.

Thousands have applied for the ability to fly drones.

Thousands sign up for FAA’s drone pilot test

The first major regulations governing civilian drone operations permit anyone 16 or older to fly for hire if they pass a written knowledge test and background check.

Health law marketplaces are in trouble. What can be done?

The law’s online marketplaces have been suffering from high-profile defections and double-digit premium increases.

Deborah DiSanzo is general manager of IBM Watson Health, IBM’s new health care division. It’s headquartered in Cambridge at 75 Binney St.

With Watson Health, IBM bets big on health care

The Cambridge-based operation is expected to employ at least 700.

Mylan Pharmaceuti-cals has faced criticism over big price hikes.

STAT

The generic EpiPen may be more profitable for Mylan

The drug maker plans to sell the generic version directly to consumers for half the cost of the branded product.

A Kate Spade store in New York, where back-to-school means more luxury items to sell.

Back-to-school divide: $195 headbands and $1 glue sticks

The fashion brand Kate Spade is most known for luxury handbags. But it is also banking on the increasingly important back-to-school shopping season.

Graduates from the Roca-CVS Pharmacy Technician Training program received their certificates at Roca. a Chelsea-based nonprofit.

CVS, nonprofit team up to train, employ young mothers

Eight young mothers graduated from a training program through a partnership of CVS Health and Roca, a Chelsea-based nonprofit.

Bingyi Chen, a Chinese immigrant who lives in Concord, has bought at least 16 units at the new Millennium Tower for $15.6 million — all in cash.

Foreign buyers at Millennium Tower show that Boston is on a world stage

Buyers from China, Greece, and Hong Kong are scooping up condos at the high-end Millennium Tower.

Harvard teams up with Tata for research, executive education

The $8.4 million agreement is the first to combine the research capabilities of Harvard’s engineering and business schools with its leadership development programs.

Jewish charity’s CFO fired amid claims of financial misdeeds

Jewish Big Brothers Big Sisters of Greater Boston didn’t name the executive in a letter to donors.

Bold Types

BC Chief Execs Club crosses the pond

For the first time in its 24-year history, the Boston College Chief Executives Club is taking its show overseas. The real reason? A football game.

“Always upbeat, great fliers make the best of their situation no matter where they’re sitting,” one new print ad from American Airlines says.

Great fliers make the ‘best of their situation,’ American Airlines suggests

American Airlines wants you to know it would really, really appreciate it if you could be polite to fellow passengers and flight attendants.

A sale of the Hershey Co. would have been subject to a trust that is the business’s controlling shareholder.

Mondelez says it ended talks to buy Hershey

Oreo cookie maker Mondelez International Inc. says it has ended discussions to buy The Hershey Co.

Out of Town News founder heartbroken over its potential departure from Harvard Square

Word that Out of Town News could be pushed out its iconic kiosk in Harvard Square as part of proposed renovations by the city was a blow to Sheldon Cohen, the newsstand’s founder, who vowed to “do whatever I can” to ensure the business remains where it is.

Tuesday’s business agenda

Consumer confidence, networking, and more notable events and things to know.

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Mylan to launch generic version of EpiPen, at half the cost

The drug maker, under fire from the public and Congress over EpiPen’s high price, plans to release a generic version.

Rents will stay stable at 875 American Legion Highway in Roslindale.

City program to preserve low-rent apartments off to slow start

The first deal under the program, announced in May, was recently secured.

Moderna Therapeutics has 11 drugs in development and two in clinical trials, the company reported recently.

With 11 drugs in pipeline, Moderna wants to raise $600m

The Cambridge biotech has already raised more than $1 billion from investors as it works to develop a class of therapies.

An introductory project management class will be offered Monday.

Monday’s business agenda

Gas prices, networking, and more notable events and things to know.

A Bridj vehicle can carry shipments as well as passengers.

Ride service Bridj plans package deliveries, with robots helping

If Matthew George has his way, a robot might deliver your groceries, maybe as soon as this year.

Facebook reduces human involvement in selection of trending topics

The social network’s move comes after a controversy over the matter earlier this year.

A view looking west along Broadway.

Is another big office building is coming to Cambridge?

The city will consider Boston Properties’ designs for a 454,000 square-foot, 19-story office building at 145 Broadway.

Netflix, with its vast library of movies and TV shows, is still the king of binge.

Consumer Reports | Product Review

Cutting the cable TV cord? Here are some options

From Acorn TV to Sling TV, there are many choices for digital video streaming services.

Tech Lab by Hiawatha Bray

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Bray writes about technology for the Business section. His Tech Lab column appears on Thursdays.

Shirley Leung

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Leung writes a business column every Wednesday and Friday. Previously she served six years as the business editor overseeing daily and Sunday coverage.

Innovation Economy by Scott Kirsner

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Kirsner’s Innovation Economy column appears in the Boston Sunday Globe, and he contributes to the Globe’s Beta Boston website.