Harvard University’s endowment chief, Jane Mendillo, earned $3.5 million in 2010, down from $4.8 million in total compensation in 2009, according to Harvard, which released its latest tax filing Friday.

The highest paid manager of the endowment in 2010 was Andy Wiltshire, who earned $5.5 million, Harvard said, for overseeing the outside firms that manage money for the nation’s largest endowment. Harvard’s top investment managers are highly compensated, routinely earning more than anyone else at the university if they beat their goals.