You can now read 5 articles in a month for free on Read as much as you want anywhere and anytime for just 99¢.

Biogen Idec, Isis to collaborate on experimental drug for myotonic dystrophy

Biogen Idec Inc., a large Weston biotechnology company known for its multiple sclerosis drugs, said Friday that it is entering another collaboration with Isis Pharmaceuticals Inc., with this collaboration focusing on an experimental drug for myotonic dystrophy, a debilitating neuromuscular disease.

In January, the two companies announced plans to work together on a potential treatment for spinal muscular atrophy.

Continue reading below

Friday’s agreement calls for California-based Isis to receive an upfront payment of $12 million, the two companies said in a press release.

Under the agreement, Isis is responsible for the discovery of a lead antisense drug candidate for the treatment of myotonic dystrophy type 1, which is also known as Steinert disease. Isis could receive up to another $200 million in a license fee and regulatory milestone payments as well as double-digit royalties on sales of the drug. Isis will be responsible for global development of the drug through the completion of Phase 2 clinical trials, with Biogen Idec providing advice on the clinical trial design and regulatory strategy, the companies said in a press release. If Biogen Idec exercises its option under the agreement, it will assume global development, regulatory, and commercialization responsibilities.

Biogen Idec said the collaboration fits its mission to “bring innovative therapies to patients with serious neurologic diseases.”

According to Isis, the collaboration allows it to expand its pipeline of drugs for rare and serious diseases with the help of Biogen Idec’s additional resources and support.

Chris Reidy can be reached at
Loading comments...
Want each day's news headlines delivered fresh to your
inbox every morning? Just connect with us
in one of the following ways:
Please enter a valid email will never post anything without asking.
Privacy Policy
Subscriber Log In

You have reached the limit of 5 free articles in a month

Stay informed with unlimited access to Boston’s trusted news source.

  • High-quality journalism from the region’s largest newsroom
  • Convenient access across all of your devices
  • Today’s Headlines daily newsletter
  • Subscriber-only access to exclusive offers, events, contests, eBooks, and more
  • Less than 25¢ a week
Marketing image of
Marketing image of