SAN JOSE, Calif. — Apple Inc. rested its patent-infringement case against Samsung Electronics Co. on Monday after putting an accountant on the witness stand who estimated the South Korean company would owe at least $2.5 billion in damages.

Terry Musika, a certified public accountant, said his estimate is based on Samsung’s sales of 22.7 million smartphones and tablet computers and revenue of $8.16 billion, starting when the Galaxy devices were introduced in June 2010.

Apple sued Samsung in April 2011, accusing it of copying patented designs. The dispute is the first to go before a federal jury in a battle being waged on four continents for dominance in a smartphone market valued at $219.1 billion.

The trial is in its third week and it will now be Samsung’s turn to call witnesses both to defend against Apple’s claims and to put on its case that Apple copied its patents. US District Judge Lucy Koh has limited each side to 25 hours to present its case.

Since the trial began July 30, Apple has called a string of witnesses to try to show that Samsung has copied the design and technology of its iPhone and ­iPad. Samsung’s lawyers have sought in cross-examination to undermine Apple’s testimony by demonstrating that its own smartphones and tables evolved through competition rather than mimicry.

Apple’s witnesses included its director of patent licensing and strategy, Boris Teksler, who testified that the company’s late cofounder, Steve Jobs, confronted Samsung executives in 2010 after they introduced the Galaxy smartphone and that Apple warned against copying the iPhone. Teksler told the jury Monday that Apple had an ­“anti-cloning” agreement with Microsoft Corp.

The jury also heard from paid expert witnesses who testified that Samsung copied Apple design features like the rounded rectangular body of the ­iPhone and functions such as “rubberbanding,” the way an ­iPad or iPhone screen seems to bounce when a user scrolls to the end of a file.

In addition to patent infringement, Apple contends that Samsung’s copying of the look of the iPhone and iPad has diluted the values of its iconic brands.

Apple used market survey research to try to show the jury that Samsung has copied its devices so closely that a consumer seeing products made by the South Korean company would actually believe them to be made by Apple. Samsung sought to demonstrate there is little actual confusion among consumers between its and ­Apple’s products.