Tech, bio firms meet resistance in Cambridge

The explosive growth that has made Cambridge one of the country’s foremost life sciences and technology hubs is meeting resistance from some residents who complain that commercial development is overwhelming city neighborhoods.

That opposition has already scored one major victory: stalling a proposed 246,000-square-foot office and lab complex near Central Square that would house drug maker Millennium Pharmaceuticals. And now more development could be in question as residents have submitted a petition to City Hall to “downzone” a number of parcels around Central Square, including the planned Millennium site, making them less suitable for large-scale development.

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