The state’s largest biotechnology trade group sent a letter to Cambridge city officials Monday opposing a proposal by neighborhood activists that would change zoning in an area around Central Square, which would potentially block large-scale development or expansion plans for life sciences companies. In the letter, Robert K. Coughlin, president of the Cambridge-based Massachusetts Biotechnology Council, noted that the city is home to more than 110 life sciences companies that are drawn to nearby research universities and hospitals.
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