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The Boston Globe


Reports of ‘fatal skin reactions’ from blockbuster Vertex drug

Vertex Pharmaceuticals Inc. said Wednesday that it will more prominently display warnings of possible side effects on the US labels of its blockbuster hepatitis C drug Incivek, following reports of a small number of fatalities.

A known side effect of Incivek is skin rash, and that was noted on the drug’s original label following its US approval in mid 2011. Cambridge-based Vertex said Wednesday that the updating of the US label “follows reports of a small number of fatal skin reactions in patients who continued to receive Incivek combination therapy after a serious skin reaction was identified.”

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