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The Boston Globe

Business

Genzyme to market new Isis drug

NEW YORK — The Food and Drug Administration approved a drug Tuesday that not only treats a rare inherited disorder that causes extremely high cholesterol levels and heart attacks by age 30 but does so using a long-sought technology that can shut off specific genes causing disease.

The drug, Kynamro, which was invented by Isis Pharmaceuticals and will be marketed by Sanofi’s Genzyme division, is unlikely to be a blockbuster. It has some worrisome side effects, and there might be no more than a few hundred people in the United States with the disease, known as homozygous familial hypercholesterolemia. Genzyme is based in Cambridge.

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