Expedia Inc. declined nearly 4.3 percent, the most in the S&P 500 — the second decline since Thursday, when the online travel agency reported a larger first-quarter loss and lowered its 2013 earnings forecast. Expedia said its costs for stock-based compensation, legal reserves, and depreciation had surged, compared to a year earlier. Expedia lost $104.2 million, or 77 cents per share. A year before it lost $3.3 million, or 2 cents. Revenue climbed 24 percent to $1.01 billion.