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Agenus slumps as clinical tests disappoint

Glaxo is studying drugs that use a compound from Lexington-based Agenus.
Associated Press/File 2010
Glaxo is studying drugs that use a compound from Lexington-based Agenus.

Agenus Inc. fell sharply after an unsuccessful clinical trial of a cancer treatment that includes its compound that is designed to make drugs more effective. British drug maker GlaxoSmithKline is studying cancer treatments that include Agenus’s SQ-21 Stimulon vaccine adjuvant. Glaxo said an experimental melanoma treatment did not meet its first goal in a mid-stage clinical trial. Glaxo is studying an immune therapy that targets MAGE-A3, an antigen found in various cancers. The therapy includes Agenus’ SQ-21 Stimulon adjuvant, extracted from the bark of an evergreen called Soapbark.

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