Two more people have died in Boston after contracting the flu — including, for the first time this season, a child — bringing the total to six.
Five of the deaths were adults over age 65, and one was a child under 6, Barbara Ferrer, executive director of the Boston Public Health Commission, said Friday evening.
The announcement was made as state and federal health data released Friday suggest that the flu season, which arrived early and fierce, may be waning here and in some other states. Massachusetts reported a drop in flu activity, as measured by the percentage of patients visiting doctor’s offices who had flu-like symptoms.
In Boston, however, “we don’t see any signs of a let-up,” Ferrer said, “which is really why we’re pushing vaccinations so hard.”
Mayor Thomas M. Menino declared a public health emergency Wednesday, and the city is working with community health centers to offer free flu vaccination clinics at numerous sites this weekend.
Unless the infections slow, the city is on track for a severe flu season, Ferrer said. “Right now, it looks alarming.”
Ferrer said the child who died “definitely had flu, but we’re not sure if there weren’t other complications that contributed to the death.”
During the milder 2011-2012 flu season, there was just one death in the city.
Earlier this week, state officials reported 18 flu deaths in Massachusetts, all adults.
Increased demand for the vaccine, fueled by calls by the mayor and health officials for most everyone to protect themselves against the more severe virus strain circulating this year, has led some Massachusetts residents to search for the immunization in vain.
Some doctors have run out of the vaccine, and the state Department of Public Health exhausted its supply this week.
Chelmsford pediatrician Mark Gilchrist said via e-mail that he did not receive an anticipated shipment of vaccine from the state Health Department for his patients, which has never happened to him in the past. He was informed earlier this week that his practice was being put on a waiting list to receive more doses as they became available.
“The best lesson to take home from this in the future,” he wrote, “is to get your influenza immunization as early as possible.”
State health officials sent an e-mail to health care providers Wednesday to let them know that they have “no remaining flu vaccine” and that they have established a waiting list for doses requested for children. They directed physicians to order immunizations from manufacturers, which say that they have remaining supplies but that delivery may take some time.
Dr. Lauren Smith, interim state health commissioner, said in an interview Friday that the Health Department gained access to some additional pediatric vaccine doses, which would be available to doctors by the middle of next week. Local boards of health that contacted the Health Department requesting vaccine this week, she added, would be receiving doses from clinics elsewhere in the state that have some extra supply.
“There are spot shortages of the flu vaccine across the country, and you may have to check several places to find a vaccine,” said Dr. Thomas Frieden, director of the US Centers for Disease Control and Prevention during a press briefing Friday. “Most of the more than 130 million doses have already been given.”
Some pharmacies have also seen shortages of Tamiflu, or oseltamivir, an antiviral medication used to treat the flu, especially in pediatric formulations. The CDC recently issued instructions to pharmacists on how to create liquid suspensions for children from adult pills, Frieden said.
The worst of the flu season, however, may be over if the latest data from the state Health Department is any indication. During the first week of January, 2.9 percent of doctor visits were for flu-like illness compared with 4.4 percent of visits during the last week in December. Whether that means the flu has peaked in Massachusetts is unknown, Smith said. The drop could also be due to a surge in patients getting treated for norovirus, a gastrointestinal illness that is sweeping the region.
While the flu has officially reached epidemic proportions around the country, the CDC said the number of states with severe outbreaks has declined, and the virus appears to have peaked in some Southern states.
Vaccine manufacturers say they have some extra supply on hand, but it may take doctors several days or even weeks to get immunizations after placing an order. MedImmune, maker of the FluMist vaccine, has more than 380,000 doses of the spray, which contains an attenuated form of the live virus and is often the vaccine of choice for children age 2 and older. “Additionally, we have a reserve order for 250,000 FluMist doses that would be shared between Medicaid’s Vaccine For Children’s program and the Department of Defense,” said spokeswoman Melissa Garcia.
Sanofi Pasteur, the biggest flu vaccine manufacturer, has injections of Fluzone available for immediate shipment for adults ages 18 to 64 and a high-dose form for those age 65 and older. The company said in a statement that shots for children over six months are out of stock and will not be shipped until the end of January.
This year’s flu vaccine appears to be somewhat less effective than in previous years, even though it is well matched to the circulating virus strains. In testing conducted by the CDC, the vaccine was found to be effective only 55 percent of the time against the H3N2 strain, according to results released Friday. This strain accounts for nearly all the flu infections in Massachusetts and has been causing more severe symptoms than other strains, including fever, cough, and body aches, as well as occasional diarrhea and vomiting.
The CDC acknowledged that, as in the past, the vaccine is even less effective in people who are elderly or have impaired immune systems that make them more susceptible to life-threatening complications occasionally seen with the flu.
“The people most susceptible to influenza are the most likely to not have effectiveness from vaccine,” Frieden said. While he called the vaccine “far from perfect,” he added that “it’s still by far the best tool we have to prevent the flu.”Deborah Kotz can be reached at email@example.com. Follow her on Twitter @debkotz2. Chelsea Conaboy can be reached at firstname.lastname@example.org. Follow her on Twitter @cconaboy.