Richard R. Tisei will release his first television advertisement, a soft biographical spot, Wednesday morning as he ­attempts to unseat US Representative John F. Tierney in the state’s most competitive House race.

The ad shows Tisei, a Wakefield realtor who has served as the top Republican in the State Senate, talking about his personal and professional connection to the congressional district. Between the close-up shots of the candidate are images of the seaport in Gloucester and of Tisei shaking hands in a diner.

There is no mention of ­Tisei’s political affiliation, a common omission for Republicans running in Massachusetts, where Democrats hold a registration advantage. Instead, ­Tisei emphasizes his ties to the community and his message of independence and bipartisanship.

“I went to school in this district,” Tisei says in the ad. “I own a small business in this district. This is a district where people are hardworking; they’re independent-minded and they want to see the same in their congressman.”

The ad is also a departure from the harsh attacks that have so far defined the race. ­Tisei has criticized Tierney over his wife’s connection to her brothers’ gambling ring, while Tierney has said Tisei will march in lockstep with the conservative leadership of the ­Republican party.

The ad will run on cable television in the Northeastern Massachusetts congressional district for at least the next four weeks, at a cost of $43,000 per week, Tisei said.

“I want to introduce myself to people the right way,” Tisei said Tuesday.

He said the ad will be ­replaced by other ads in about a month.