One person died and three others were injured in a head-on collision Sunday night on Route 28 in the Cotuit section of Barnstable, police said. The accident occurred at 10:54 p.m. near 4300 Falmouth Road. The road was closed for two hours to remove the two heavily damaged vehicles, which came to rest in the westbound lane, said Barnstable Police Officer Kevin Donovan. The operators of the two vehicles were both transported to Cape Cod Hospital, where one was pronounced dead. The surviving operator’s two passengers were transported to Falmouth Hospital and South Shore Hospital. All three have injuries that are not considered life-threatening, Donovan said. The names of the victims have not been released. The accident is under investigation by Barnstable police.