Talk show host, entrepreneur and entertainer Oprah Winfrey will be Harvard University’s principal speaker at the afternoon exercises of Harvard’s 362nd Commencement, the university announced Monday morning.

“Oprah’s journey from her grandmother’s Mississippi farm to becoming one of the world’s most admired women is one of the great American success stories,” Harvard President Drew Faust said in a statement posted on the Harvard Gazette website. “She has used her extraordinary influence and reach as a force for good in the world, with a constant focus on the importance of educational opportunity and the virtues of serving others.”