Two people suffered life-threatening injuries in a three-vehicle crash on the Massachusetts Turnpike in Oxford early Monday morning, State Police said.
State troopers responded at 4:32 a.m. to reports of a serious crash involving a pickup truck, a tractor-trailer, and a sedan, State Police said. Three other people sustained injuries that were not considered life-threatening.
The crash occurred when a pickup truck operated by a 26-year-old Brookline man left the roadway and struck the median guardrail, according to the State Police.
The truck rolled over and stopped in the center lane. The driver and his 25-year-old male passenger were not seriously injured in the initial crash.
But as the driver crawled out of his vehicle into the roadway, he and the truck were struck by a tractor-trailer, State Police said. The pickup driver suffered life-threatening injuries and was transported by ambulance to the University of Massachusetts Medical Center in Worcester. His passenger was taken to UMass Medical with injuries not believed to be life-threatening.
After hitting the pickup truck, the tractor-trailer struck a sedan passing in the lane to the left, State Police said. The sedan’s driver, 26, and passenger, 27, sustained serious, but not life-threatening injuries, and were taken by ambulance to UMass Medical Center.
The driver of the tractor-trailer, a 26-year-old man from Rhode Island, suffered life-threatening injuries and was flown by medical helicopter to UMass Medical, according to State Police.
Authorities did not release the names of any of the those involved in the crash.
The turnpike was closed eastbound and westbound near the Charlton line for 15 minutes following the crash to accommodate the medical helicopter.
Three of four eastbound lanes were then closed for rescue operations, significantly affecting traffic.
All lanes were reopened by about 8:30 a.m.
Troopers from the Charlton barracks were assisted by the Oxford and Auburn fire departments at the scene. Troopers, with the help of State Police crime scene experts, are investigating.Catalina Gaitan can be reached at catalina.gaitan@
globe.com. Follow her on Twitter at @catalina_gaitan.