Metro

Explosion in Tewksbury sends three burn victims to hospitals

An explosion at a Tewksbury home Tuesday night caused a fire that sent three burn victims to area hospitals, authorities said.

The explosion and subsequent two-alarm fire occurred around 9:20 p.m. at 22 Astle St., said Tewksbury police.

State Fire Marshal Stephen Coan said his office was called to assist with an “incident of some magnitude” at the house. The cause of the blast is under investigation, he said.

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Tewksbury Fire Department and mutual aid ambulances from nearby areas responded to the scene.

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Multiple medical flights carried the victims — two males and one female — to Boston hospitals, authorities said. The three victims are being treated for burns, said Captain Jon Viscione of the Tewksbury Fire Department. Responders were not able to immediately confirm the extent of their injuries.

The two-story clapboard home was built in 1800, according to Tewksbury town records. Files indicate it is owned by Herbert L. Mulno Jr. and Mildred A. Mulno.

Additional details were not available late Tuesday night.

Travis Andersen of the Globe staff contributed to this report. Jennifer Smith can be reached at jennifer.smith@globe.com.