GOODWELL, Okla. — Three Union Pacific Railroad crew members were missing after two freight trains collided Sunday in the Oklahoma Panhandle.

An eastbound train and a westbound train, each carrying vehicles, crashed about 10:08 a.m. Sunday near Goodwell, said Raquel Espinoza, a regional spokeswoman for Union Pacific.

A two-member crew was aboard each train, and officials were unable to account for two engineers and a conductor, Espinoza said.

The other conductor appeared to be uninjured, and officials were interviewing him about what happened, she said. ‘‘We’re doing everything we can to find the rest of the crew,’’ Espinoza said.

The westbound train had three locomotives and 80 railcars that were carrying motor vehicles, she said.

Two of that train’s locomotives and a locomotive from the eastbound train caught fire after the collision, she said.

One train was hauling a resin solution, but Espinoza said that load did not catch fire and was doused with water as a precaution.

Firefighters were called to extinguish the blaze, which was burning in a sparsely populated area, said Harold Tyson, the Texas County emergency management director. No evacuations were ordered, he said.

Firefighters struggled to stay hydrated as temperatures climbed past 100 degrees, but no injuries to emergency workers had been reported, Tyson said.