Nation

$2m study will map Alzheimer’s DNA

MINNEAPOLIS -- Working with $2 million in new grants to be announced this week, researchers for the Alzheimer’s Disease Neuroimaging Initiative will, for the first time, start mapping the DNA of 800 participants in a study attempting to find the root causes of memory loss.

The goal is to see if physical changes from Alzheimer’s can be matched to genetic disparities, which can then be compared with findings from healthy people.

Advertisement

While about 10 genes are already linked to the condition, crucial details about genetic variations and how they interact remain unknown, said Robert Green, a medical geneticist at Brigham and Women’s Hospital and Harvard Medical School in Boston who is coordinating the sequencing efforts.

The research initiative, which is being funded by the US government, nonprofit groups, and private industry, began tracking physical and mental changes in people ages 60 and older in 2004.

Get Ground Game in your inbox:
Daily updates and analysis on national politics from James Pindell.
Thank you for signing up! Sign up for more newsletters here

The new grants are from the Alzheimer’s Association and the Brin Wojcicki Foundation, a charitable organization. Both are nonprofits.

The genetic samples have already been gathered, the researchers said, and will be sequenced at Illumina, the gene-mapping company based in San Diego.

Bloomberg News

Loading comments...
Real journalists. Real journalism. Subscribe to The Boston Globe today.
We hope you've enjoyed your free articles.
Continue reading by subscribing to Globe.com for just 99¢.
 Already a member? Log in Home
Subscriber Log In

We hope you've enjoyed your 5 free articles'

Stay informed with unlimited access to Boston’s trusted news source.

  • High-quality journalism from the region’s largest newsroom
  • Convenient access across all of your devices
  • Today’s Headlines daily newsletter
  • Subscriber-only access to exclusive offers, events, contests, eBooks, and more
  • Less than 25¢ a week
Marketing image of BostonGlobe.com
Marketing image of BostonGlobe.com