CINCINNATI — Four people were killed early Sunday when a minivan carrying a family leaving a Christmas party went the wrong way on a southwestern Ohio highway and hit another minivan whose driver and family were going to see grandparents for the holidays, police said.

The 2:30 a.m. head-on collision on Interstate 75 near Franklin claimed the lives of three adults and a 7-year-old boy and critically injured two other children, said Ohio State Patrol Sergeant Stan Jordan.