ASSIUT, Egypt — A speeding train crashed into a bus carrying Egyptian children to their kindergarten in central Egypt on Saturday, killing at least 51 and prompting a wave of anger against the government in Cairo.

More than 50 children between 4 and 6 years old were among about 65 people on board when the bus was hit, a security official said. The official said it appeared the railroad crossing was not closed as the train sped toward it.