VATICAN CITY — Pope Francis on Sunday gave the Catholic Church new saints, including hundreds of 15th-century martyrs who were beheaded for refusing to convert to Islam, as he led his first canonization ceremony Sunday in a packed St. Peter’s Square.
The ‘‘Martyrs of Otranto’’ were 813 Italians who were slain in the southern Italian city in 1480 for defying demands to renounce Christianity by Turkish invaders who overran the citadel.
Their approval for sainthood was decided upon by Francis’ predecessor, Benedict XVI, in a decree read at the ceremony in February where the former pontiff announced his retirement.
Shortly after his election in March, Francis called for more dialogue with Muslims, and it was unclear how the granting of sainthood to the martyrs would be received. Islam is a sensitive subject for the church, and Benedict stumbled significantly in his relations with the Muslim community.
The first pontiff from South America also gave Colombia its first saint: a nun who toiled as a spiritual guide to indigenous people in the 20th century.
The Argentine pope held out Laura of St. Catherine of Siena Montoya y Upegui as a potential source of inspiration to the country. Colombia has begun a peace process after decades-long conflict between rebels and government forces.
Francis prayed that ‘‘Colombia’s beloved children continue to work for peace and just development of the country.’’
He also canonized another Latin American woman. Maria Guadalupe Garcia Zavala, a Mexican who dedicated herself to nursing the sick, helped Catholics avoid persecution during a government crackdown on the faith in the 1920s.
Also known as Mother Lupita, she hid the Guadalajara archbishop in an eye clinic for more than a year after fearful local Catholic families refused to shelter him.
Francis prayed that the new Mexican saint’s intercession could help the nation ‘‘eradicate all the violence and insecurity,’’ an apparent reference to years of bloodshed linked to drug-trafficking clans.