The Cannons dropped their second straight game in frustrating fashion, 13-10, to the Long Island Lizards before a record crowd of 11,894 at Harvard Stadium Saturday night.

The Cannons, who dawned purple and pink jerseys in support of the March of Dimes, managed a season-low 10 goals.

“It’s disappointing to come out here and play the way we did tonight,’’ said Boston coach Steve Duffy. “We had a great crowd and we felt good going into the game. You have to give Long Island a lot of credit. They took us out of what we wanted to do and their goalie played excellent.’’

The Lizards’ Drew Adams made 16 saves.

The Cannons entered the fourth quarter leading, 10-9, but the Lizards took the lead on a two-point shot by Chris Passavia and never looked back.

“They were just persistent,’’ said Cannons goalie Jordan Burke, who had eight saves. “They were patient with the ball on offense and got good looks. Offensively, we just couldn’t get one by Drew. It was just a tough game all around.’’

The Cannons’ leading scorer, Paul Rabil, put eight shots on Adams, but walked away with one goal and five assists.

“[Adams] is a goalie that anticipates the ball and guesses,’’ said Rabil. “When you guess right, you make the save every time and it’s frustrating. The book on Adams is to shoot where he is because he jumps to the ball. We just didn’t do that. We were shooting to good spots, but he’s the best guesser in the league and he did a good job.’’

Boston took a quick 2-0 lead, but the Lizards countered with the next three strikes.

In the final minute of the first, back-to-back saves by Burke led to Brian Farrell’s second goal and a 3-3 tie after one period.

Greg Gurenlian won the opening draw of the second half and took it straight to the net to give the Lizards the lead seven seconds in.

Gurenlian, who was Major League Lacrosse’s Defensive Player of the Week last week, won 11 of 24 faceoff attempts against the Cannons’ Chris Eck.

With the shot clock winding down midway through the second quarter, Long Island’s Max Seibald (two goals), beat Burke with a two-point shot from 20 yards to give the Lizards a 6-4 edge.

The goal was just the second two-pointer to get past Burke this season, but it wouldn’t be the last on this night.

The Cannons rallied to score the next four goals, but ended the half on a sour note, allowing a goal by Albert Maione with 1.2 seconds remaining to cut Boston’s lead to 8-7.

Rabil’s lone goal, his 14th of the season, was the Cannons’ last and came with nine minutes to play in the third quarter. The strike put the Cannons up, 10-7.

The Lizards rallied to score the final two goals in the period and entered the fourth trailing, 10-9.

Long Island continued the momentum in the fourth, taking their first lead since the final minute of the first quarter, when Passavia beat Burke with an unassisted two-point shot with 10:38 to play.

Tommy Palasek and rookie attackman Matt Gibson (two goals, one assist) added late goals to end any comeback chances for the Cannons.

“A lot of our wounds were self-inflicted,’’ said Burke. “We just have to try to regroup and clean things up a little bit.

“We just need to focus on ourselves and get ready for next week.’’