Edwin Encarnacion hit his fifth career grand slam, J.P. Arencibia homered and drove in four runs, and the Blue Jays beat Baltimore, 12-6, on Thursday night in Toronto, spoiling the debut of Orioles righthander Kevin Gausman.
Brandon Morrow (2-3) allowed six runs and a season-high 10 hits in seven-plus innings. He walked one and struck out five.
Baltimore’s Chris Davis hit his major league-leading 15th home run, a leadoff shot in the fourth. Nick Markakis and Adam Jones hit back-to-back homers off Morrow in the eighth but it wasn’t enough for the Orioles, who lost for the seventh time in nine games.
‘‘It’s frustrating for me to go out, give up the two home runs without getting an out there in the eighth,’’ Morrow said. ‘‘It’s a good win, but it put a sour taste in my mouth.’’
Baltimore’s Manny Machado went 3 for 4 with three doubles, boosting his major league-leading total to 21.
Machado gave the Orioles an early lead with a two-run double in the third. Davis made it 3-0 by homering on Morrow’s first pitch of the fourth, but the Blue Jays rallied with two runs off Gausman in the bottom half. Adam Lind and Arencibia led off with consecutive doubles and Emilio Bonifacio hit a sacrifice fly.
Arencibia put the Blue Jays in front with a two-out, first pitch homer in the fifth, his 11th.
The fourth overall pick in the 2012 draft, Gausman (0-1) allowed four runs and seven hits in five innings. He walked two and struck out five.
‘‘Definitely a learning experience for me but it was awesome,’’ Gausman said. ‘‘It was everything I could have imagined and more.”
Baltimore reliever Troy Patton was replaced after issuing back-to-back two-out walks in the sixth. Pedro Strop came on and walked Jose Bautista before Encarnacion homered off the left- field foul pole, Toronto’s first grand slam this season.
Angels 5, Royals 4 — Mike Trout, Chris Iannetta, and Albert Pujols hit solo home runs, and Mark Trumbo hit a two-run shot to help visiting Los Angeles hold off Kansas City.
Joe Blanton got his first victory of the season after going 0-7 in his first nine starts. He held the Royals to seven hits and two runs in 6⅓ innings.
Ervin Santana (3-4), who spent 12 seasons in the Angels organization before being traded during the offseason to the Royals, struck out eight without a walk, but allowed five runs and eight hits — four of which were homers.
Salvador Perez and George Kottaras had RBI singles in the ninth inning, but Kansas City fell short in the end.
The Royals have lost 13 of their last 18 games to fall two games below .500, matching their worst record. They have scored three or fewer runs in 10 of the losses.
Tigers 7, Twins 6 — Prince Fielder bounced a tiebreaking single off Jared Burton’s glove in the eighth inning, leading the hosts to a come-from-behind victory over Minnesota.
Omar Infante started the inning with a single and was bunted to second by Torii Hunter. Ron Gardenhire then had Miguel Cabrera intentionally walked, but Fielder foiled the plan with a grounder that Burton (0-2) deflected past second baseman Brian Dozier.
Cabrera drove in three runs, including his sixth homer in four games. Cabrera has now matched a career high by homering in four straight games. He has also walked five times in the four games, and Fielder has followed all five with hits, driving in seven more runs.
Pirates 4, Cubs 2 — Andrew McCutchen had three hits and two RBIs to lead host Pittsburgh past Chicago for its fourth straight win.
Leadoff hitter Starling Marte singled and scored in each of the first two innings as Pittsburgh built a 4-0 lead. The Pirates moved a season-best 11 games over .500 with their 11th victory in 13 games.