Notre Dame took advantage of a trick play that backfired, as well as four pass interference calls and a holding penalty that kept drives alive, to defeat Michigan State for the third straight time.
The mistakes led to all of Notre Dame’s points in Saturday’s 17-13 victory in South Bend, Ind., including two on the winning drive after a pass by Michigan State receiver R.J. Shelton led to an interception by Matthias Farley, setting up the go-ahead touchdown.
Michigan State coach Mark Dantonio said he couldn’t ever recall so many defensive pass interference calls in one game.
‘‘I’ve been coaching 30-plus years, no. Never,’’ he said. ‘‘I guess that’s where we should stop.’’
The costliest mistake, though, likely was the interception thrown by Shelton that shifted momentum Notre Dame’s way. Shelton threw into double coverage and Farley picked it off.
The Spartans (3-1) were called for two pass interference calls on the ensuing drive, allowing Notre Dame to maintain possession. The Irish scored moments later when Cam McDaniel ran 7 yards to give ND a 17-10 lead with 14:44 left.
The win gave the Irish 10 straight at home for the first time since 1999, when Bob Davie was coach.
Florida 31, Tennessee 17 — The second Jeff Driskel started waving for help, Florida coach Will Muschamp knew it was bad. It turned out to be the worst-case scenario.
Driskel broke his lower right leg in the first quarter of the 19th-ranked Gators’ victory over the visiting Volunteers, a season-ending injury that thrust seldom-used backup Tyler Murphy onto the field for the most significant action of his four-year career.
Murphy had a 52-yard touchdown throw to Solomon Patton and Florida (2-1, 1-0 SEC) won its ninth consecutive game in the series. Tennessee (2-2, 0-1) gave redshirt freshman quarterback Nathan Peterman his first career start but he committed three turnovers before being pulled at halftime.
Northwestern 35, Maine 21 — Damien Proby and Dean Lowry each had an interception return for a touchdown to help the No. 18 Wildcats (4-0) dodge an upset at the hands of the visiting Black Bears (3-1) of the FCS.
Marcus Wasilewski was 25 of 40 for 237 yards with two TDs for Maine, which had a 379-373 advantage in total yards. But his interceptions, at the end of the first half and beginning of the second, helped Northwestern pull away.
Alabama 31, Colorado State 6 — Kenyan Drake set up one touchdown with a blocked punt and scored on a 3-yard run, AJ McCarron threw a 30-yard touchdown to DeAndrew White in the fourth quarter, and the No. 1 Crimson Tide (3-0) pulled away to knock off the visiting Rams (1-3).
Ohio State 76, Florida A&M 0 — Kenny Guiton again starred in place of the injured Braxton Miller, setting a school record with six touchdown passes — all in the first half — to lead the No. 4 Buckeyes (4-0) past the visiting Rattlers (1-3).
Stanford 42, Arizona State 28 — Kevin Hogan passed for two TDs and Tyler Gaffney ran for a pair as the fifth-ranked Cardinal (3-0, 1-0 Pac-12) built a 29-0 halftime lead and held off the No. 23 Sun Devils (2-1, 1-0) in Stanford, Calif.
LSU 35, Auburn 21 — Jeremy Hill rushed for a career-high 184 yards and tied a career high with three touchdowns to help sixth-ranked LSU (4-0, 1-0 SEC) get past Auburn (3-1, 1-1) in Baton Rouge, La.
Louisville 72, Florida International 0 — Teddy Bridgewater threw four touchdown passes and the defense allowed a school-record 30 yards, helping the seventh-ranked Cardinals (4-0) blow out the visiting Panthers (0-4).
Georgia 45, North Texas 21 — Aaron Murray threw for 408 yards and three touchdowns and ran for another score to lead the No. 9 Bulldogs (2-1) past the pesky Mean Green (2-2) in Athens, Ga.
Texas A&M 42, SMU 13 — Johnny Manziel accounted for 346 yards and three TDs in just more than a half to help the No. 10 Aggies (3-1) cruise past the visiting Mustangs (1-2). Manziel had 244 yards passing with a TD and ran for 102 yards and two more scores.
Washington 56, Idaho State 0 — Keith Price threw for 213 yards and three touchdowns in less than a half, Deontae Cooper scored his first career touchdown after three major knee surgeries, and the No. 17 Huskies (3-0) routed the FCS Bengals (2-1) in Seattle.
Baylor 70, La.-Monroe 7 — Bryce Petty threw for 351 yards with four touchdowns as the No. 20 Bears (3-0) became the first FBS team since LSU in 1930 to open with at least 60 points in three consecutive games, according to STATS.
Wisconsin 41, Purdue 10 — Melvin Gordon ran for three touchdowns and the No. 24 Badgers (3-1, 1-0) opened Big Ten play with a rout of the visiting Boilermakers (1-3, 0-1).
Texas Tech 33, Texas State 7 — Backup quarterback Davis Webb threw for two touchdowns and 310 yards to lead the No. 25 Red Raiders (4-0) over the visiting Bobcats (2-1).