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NFL Update: Week 6 preview

MATTHEW STAFFORD: Most yardage by a QB after 50 games

Mike Roemer/Associated Press

MATTHEW STAFFORD: Most yardage by a QB after 50 games

A look at Week 6’s NFL matchups:

Green Bay at Baltimore

Time: 1 p.m., Fox. Line: Packers by 3.

Records: Packers 2-2 (2-2 vs. spread), Ravens 3-2 (3-2 vs. spread).

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Comments: Packers haven’t been to Charm City since 2005, when Brian “Pop Warner” Billick’s Ravens handed out a 48-3 beating . . . Cheesehead QB Aaron Rodgers has won 8 of last 11 vs. AFC foes, throwing for 27 TDs and 5 INTs . . . Ravens QB Joe Flacco is 10-0 with 16 TDs and 3 INTs vs. NFC opponents at home . . . Random stat: Green Bay is 8-0 when LB A.J. Hawk has an INT . . . Baltimore’s Ray Rice has rushed for 100-plus yards in two straight. Ravens are 14-3 when he does that . . . Player to watch: Green Bay rook Eddie Lacy rushed for 99 yards last week.

Key injuries: PACKERS: OUT: CB Casey Hayward (hamstring), LB Brad Jones (hamstring), LB Clay Matthews (hamstring), RB James Starks (knee), G Greg Van Roten (foot). QUESTIONABLE: CB Jarrett Bush (hamstring). PROBABLE: LB Sam Barrington (hip), LB Andy Mulumba (ankle), DT Ryan Pickett (hand). RAVENS: DOUBTFUL: NT Terrence Cody (knee). QUESTIONABLE: CB Chykie Brown (thigh), WR Marlon Brown (thigh), S Michael Huff (back), C Ryan Jensen (foot), WR Jacoby Jones (knee), LB Albert McClellan (shoulder), DT Haloti Ngata (hip), G Kelechi Osemele (back), RB Bernard Pierce (thigh), DT Marcus Spears (knee), WR Brandon Stokley (thigh).

Oakland at Kansas City

Time: 1 p.m. Line: Chiefs by 8.

Records: Raiders 2-3 (4-1 vs. spread), Chiefs 5-0 (4-1 vs. spread).

Comments: KC leads series, 53-50-2 . . . Chiefs are first team to start 5-0 the season after losing 14 games . . . Chiefs have found themselves a QB in Alex Smith, who is 24-5-1 as a starter with 37 TDs and 13 INTs . . . Raiders have found one, too, in Terrelle Pryor, who is 37 of 51 for 502 yards with 3 TDs and zero INTs in last two . . . Oakland’s Darren McFadden has rushed for 100-plus yards in two straight vs. Chiefs . . . KC LB Tamba Hali has 6 career sacks vs. Raiders . . . Player to watch: Oakland’s Charles Woodson recorded his NFL-record 13th defensive TD last week.

Key injuries: RAIDERS: OUT: S Tyvon Branch (ankle), T Menelik Watson (calf), C Stefen Wisniewski (knee). QUESTIONABLE: RB Rashad Jennings (hamstring), LB Kaluka Maiava (hamstring), RB Darren McFadden (hamstring), DT Stacy McGee (shoulder), T Tony Pashos (groin). PROBABLE: RB Marcel Reece (knee). CHIEFS: OUT: TE Travis Kelce (knee). DOUBTFUL: TE Anthony Fasano (ankle, knee). QUESTIONABLE: CB Brandon Flowers (knee). PROBABLE: G Jeff Allen (groin), WR Donnie Avery (shoulder), RB Jamaal Charles (toes), P Dustin Colquitt (right knee), T Eric Fisher (concussion), LB Justin Houston (concussion), TE Sean McGrath (knee), LB Dezman Moses (toe), G Geoff Schwartz (triceps), RB Anthony Sherman (knee).

Washington at Dallas

Time: 8:30 p.m., NBC. Line: Cowboys by 5.

Records: Redskins 1-3 (1-3 vs. spread), Cowboys 2-3 (4-1 vs. spread).

Comments: You just knew Tony Romo was going to throw that INT last week, didn’t you? OK, maybe you thought he’d fumble . . . Have to give the man credit: He did throw for a franchise-record 505 yards and 5 TDs . . . Redskins QB Robert Griffin III was 2-0 vs. Cowboys with a 111.7 passer rating last season. When will we see that guy again? . . . Washington’s Santana Moss is 113 receiving yards shy of 10,000 . . . Cowboys lead slate, 62-40-2 . . . Redskins’ Brian Orakpo has a sack in three straight . . . Player to watch: Dallas WR Dez Bryant has 6 TD catches in last four games.

Key injuries: REDSKINS: DOUBTFUL: NT Chris Neild (calf). QUESTIONABLE: LB Brandon Jenkins (ankle), TE Logan Paulsen (knee). PROBABLE: TE Fred Davis (ankle), K Kai Forbath (right groin), RB Alfred Morris (ribs), TE Jordan Reed (thigh). COWBOYS: OUT: RB Lance Dunbar (hamstring), DE Edgar Jones (groin). QUESTIONABLE: LB Justin Durant (groin). PROBABLE: WR Miles Austin (hamstring), S Barry Church (nose), WR Dwayne Harris (hip), DT Jason Hatcher (neck).

Indianapolis at San Diego

Time: Monday, 8:40 p.m., ESPN. Line: Colts by 1½.

Records: Colts 4-1 (3-2 vs. spread), Chargers 2-3 (3-1-1 vs. spread).

Comments: Colts coming off their most impressive win of the post-Peyton Era as Andrew Luck posted his ninth game-winning drive in fourth quarter or OT (most by a player through first 21 games since 1970) . . . Chargers QB Philip Rivers has thrown for 400-plus yards in 3 of 4 . . . Indy’s Reggie Wayne is 4 catches shy of 1,000 (pretty sure 732 of them came against Patriots) . . . Chargers TE Antonio Gates has 438 receiving yards . . . Colts LB/DE Robert Mathis has 9½ sacks through five games . . . Player to watch: SD’s Danny Woodhead leads all RBs with 31 catches (insert sad face here).

Key injuries: COLTS: DNP: S LaRon Landry (ankle), LB Bjoern Werner (foot). LIMITED: LB Erik Walden (elbow). FULL: RB Stanley Havili (ankle), DT Ricky Jean Francois (groin). CHARGERS: DNP: LB Donald Butler (groin), LB Jarret Johnson (hamstring), CB Richard Marshall (groin), G Chad Rinehart (toe). LIMITED: T D.J. Fluker (calf). FULL: RB Ryan Mathews (concussion), CB Johnny Patrick (chest).

St. Louis at Houston

Time: 1 p.m. Line: Texans by 7½.

Records: Rams 2-3 (1-4 vs. spread), Texans 2-3 (0-5 vs. spread).

Comments: Rams’ Chris “son of Howie” Long has 11½ sacks in last 12 games, while fellow DE Robert Quinn has 6 sacks in his last six games . . . Houston’s Arian Foster is 89 rushing yards shy of 5,000 . . . St. Louis’s Zac Stacy rushed for 78 yards in first career start last week (you might be able to get 78 vs. Jags) . . . Player to watch: Texans QB Matt Schaub has thrown a pick-6 in four straight games.

Key injuries: RAMS: DOUBTFUL: CB Cortland Finnegan (thigh). QUESTIONABLE: DE William Hayes (knee), T Rodger Saffold (knee), RB Zac Stacy (chest). PROBABLE: DT Matt Conrath (concussion). TEXANS: OUT: LB Tim Dobbins (hamstring). QUESTIONABLE: WR Andre Johnson (shin), WR Keshawn Martin (shoulder). PROBABLE: LB Bryan Braman (neck, knee), G Brandon Brooks (toe), T Duane Brown (toe), LB Brian Cushing (knee), RB Arian Foster (thumb, chest), T Ryan Harris (elbow), CB Brice McCain (knee), C Chris Myers (biceps), T Derek Newton (knee), S Eddie Pleasant (ankle), WR DeVier Posey (Achilles’), S Ed Reed (knee), LB Darryl Sharpton (foot), DE Antonio Smith (quadriceps), G Wade Smith (knee), RB Ben Tate (elbow), DE J.J. Watt (nose).

Cincinnati at Buffalo

Time: 1 p.m. Line: Bengals by 6½.

Records: Bengals 3-2 (3-1-1 vs. spread), Bills 2-3 (3-2 vs. spread).

Comments: Mammoth Cincinnati TEs Jermaine Gresham and Tyler Eifert have combined for 39 receptions (too soon?) . . . Bills, who seek third straight home win, will start Thad Lewis at QB (currently owned by zero Fantasy geeks worldwide) . . . Bengals are 10-1 when Andy Dalton posts a 100-plus passer rating . . . Player to watch: Buffalo’s Super Mario Williams has 7½ sacks in last four games.

Key injuries: BENGALS: QUESTIONABLE: LB Michael Boley (hamstring), CB Brandon Ghee (thigh), CB Leon Hall (hamstring), DE Michael Johnson (concussion). PROBABLE: G Mike Pollak (knee), T Andre Smith (shoulder). BILLS: OUT: CB Ron Brooks (foot), QB EJ Manuel (knee). QUESTIONABLE: CB Stephon Gilmore (wrist), WR Stevie Johnson (back, not injury related), RB C.J. Spiller (ankle). PROBABLE: S Jairus Byrd (foot), WR Marcus Easley (ribs), WR Marquise Goodwin (hand), DT Kyle Williams (Achilles’).

Detroit at Cleveland

Time: 1 p.m. Line: Lions by 2½.

Records: Lions 3-2 (3-2 vs. spread), Browns 3-2 (3-2 vs. spread).

Comments: Detroit’s Reggie Bush is averaging 125.5 yards from scrimmage (third best in NFL) . . . Browns are aiming for their fourth straight win (you read that right) . . . Lions’ Matthew Stafford’s 14,331 yards are most ever by QB in first 50 games . . . Detroit’s Ndamukong Suh has 24 sacks since 2010 . . . Player to watch: Cleveland WR Josh Gordon has 18 catches for 303 yards in his last three games.

Key injuries: LIONS: OUT: WR Nate Burleson (forearm), RB Theo Riddick (concussion), TE Tony Scheffler (concussion). DOUBTFUL: T Jason Fox (knee). QUESTIONABLE: WR Calvin Johnson (knee). PROBABLE: S Louis Delmas (knee), CB Chris Houston (hamstring), LB Ashlee Palmer (ankle), S Glover Quin (ankle). BROWNS: OUT: QB Brian Hoyer (knee), DE Billy Winn (quadriceps). QUESTIONABLE: LB Quentin Groves (ankle), LB Jabaal Sheard (knee). PROBABLE: DE Desmond Bryant (illness), DE John Hughes (knee), RB Chris Ogbonnaya (concussion), T Joe Thomas (elbow).

Carolina at Minnesota

Charles Rex Arbogast/Associated Press

CORDARRELLE PATTERSON: NFL leader in kickoff return average

Time: 1 p.m. Line: Vikings by 2.

Records: Panthers 1-3 (1-3 vs. spread), Vikings 1-3 (2-2 vs. spread).

Comments: Carolina CB Captain Munnerlyn (great name!) had a sack, a forced fumble, and a fumble recovery vs. Minnesota on 10/30/2011 . . . Vikings LB Erin Henderson (greater name!) is lone NFLer with 2 sacks and 2 INTs this season . . . Panthers are 18-4 when DeAngelo Williams gets 18-plus carries . . . Player to watch: Minny rookie Cordarrelle Patterson leads NFL with 33.8-yard kickoff return average.

Key injuries: PANTHERS: OUT: CB D.J. Moore (knee). DOUBTFUL: RB Kenjon Barner (foot), DT Dwan Edwards (hamstring), S Robert Lester (hamstring). PROBABLE: DT Colin Cole (shoulder), S Quintin Mikell (ankle), TE Greg Olsen (foot). VIKINGS: QUESTIONABLE: TE Rhett Ellison (knee), K Blair Walsh (left hamstring). PROBABLE: CB Chris Cook (groin), RB Adrian Peterson (not injury-related), QB Christian Ponder (rib), S Jamarca Sanford (hamstring), WR Joe Webb (illness), DT Kevin Williams (knee).

Pittsburgh at New York Jets

Time: 1 p.m., CBS Line: Even.

Records: Steelers 0-4 (0-4 vs. spread), Jets 3-2 (4-1 vs. spread).

Comments: Steelers have dominated this series, 16-4 . . . Jets are 2-0 at home . . . NY QB Mark Sanchez had season-ending shoulder surgery last week (no word on whether the doc removed that silly head band, though) . . . NYJ RB Bilal Powell rushed for career-high 149 in last home game . . . Player to watch: Pittsburgh QB Ben Roethlisberger is 4-2 vs. Jets and needs 4 TD passes to reach 200.

Key injuries: STEELERS: OUT: WR Markus Wheaton (finger). PROBABLE: QB Ben Roethlisberger (right finger). JETS: OUT: WR Santonio Holmes (foot, hamstring), CB Dee Milliner (hamstring). DOUBTFUL: TE Kellen Winslow (knee). QUESTIONABLE: T Oday Aboushi (knee), CB Antonio Cromartie (hip, knee). PROBABLE: S Antonio Allen (finger), G Willie Colon (knee), LB Quinton Coples (ankle), DT Kenrick Ellis (not injury-related), WR Clyde Gates (knee), RB Mike Goodson (illness), RB Chris Ivory (hamstring), S Jaiquawn Jarrett (knee), WR David Nelson (hamstring), DT Sheldon Richardson (shoulder), CB Darrin Walls (shoulder).

Philadelphia at Tampa Bay

Time: 1 p.m. Line: Eagles by 2½.

Records: Eagles 2-3 (2-3 vs. spread), Buccaneers 0-4 (1-3 vs. spread).

Comments: Philly QB Nick Foles passed for 381 yards and a pair of TDs in win over Bucs last December. He gets the start Sunday for Michael Vick (hamstring) . . . Tampa Bay’s Doug Martin rushed for 128 yards and a score in December meeting . . . Bucs’ Mark Barron has team-high 30 tackles . . . Player to watch: Eagles LeSean McCoy has NFL highs in rushing yards (514) and yards from scrimmage (700).

Key injuries: EAGLES: QUESTIONABLE: TE James Casey (groin), QB Michael Vick (hamstring). PROBABLE: LB Connor Barwin (knee), CB Brandon Boykin (groin), S Patrick Chung (shoulder), QB Nick Foles (groin), P Donnie Jones (left foot), T Jason Peters (finger), RB Chris Polk (ankle). BUCCANEERS: OUT: CB Michael Adams (knee). QUESTIONABLE: CB Johnthan Banks (illness), G Carl Nicks (foot), WR Mike Williams (hamstring). PROBABLE: S Mark Barron (hamstring), G Gabe Carimi (illness), TE Tom Crabtree (ankle), S Dashon Goldson (foot), DT Derek Landri (knee), DE Steven Means (shoulder), CB Rashaan Melvin (hamstring).

Jacksonville at Denver

Time: 4:05 p.m. Line: Broncos by 26½.

Records: Jaguars 0-5 (0-5 vs. spread), Broncos 5-0 (3-2 vs. spread).

Comments: Denver put up 51 points last week vs. Dallas. Jaguars have put up 51 points this season . . . Broncos have won 16 straight regular-season games and No. 17 is about as certain as a late-game Romo giveaway . . . New England’s Wes Welker (oops) Denver’s Wes Welker’s next catch will be No. 800 . . . Jaguars’ Cecil Shorts is averaging 82.2 yards receiving per game . . . Player to watch: Broncos DE Robert Ayers has career-high 4½ sacks.

Key injuries: JAGUARS: OUT: WR Stephen Burton (concussion), QB Blaine Gabbert (hamstring), CB Dwayne Gratz (ankle), TE Marcedes Lewis (calf), DE Jeremy Mincey (concussion). PROBABLE: WR Mike Brown (back), LB Geno Hayes (hip flexor), DT Sen’Derrick Marks (knee), DT Roy Miller (shoulder), WR Cecil Shorts (groin). BRONCOS: DOUBTFUL: DE Robert Ayers (shoulder), LB Wesley Woodyard (neck). PROBABLE: CB Champ Bailey (foot), WR Eric Decker (ankle), TE Joel Dreessen (knee), CB Chris Harris (concussion), RB Ronnie Hillman (ankle), G Chris Kuper (ankle), LB Paris Lenon (thigh), K Matt Prater (right calf), C Manny Ramirez (ankle).

Tennessee at Seattle

Time: 4:05 p.m. Line: Seahawks by 13.

Records: Titans 3-2 (3-1-1 vs. spread), Seahawks 4-1 (4-1 vs. spread).

Comments: Seahawks WR Sidney Rice has 5 TDs in last seven games vs. AFC opponents . . . Tennessee is 24-9 when Chris Johnson rushes for at least 100 yards . . . Titans DT Ropati Pitoitua (yeah, I can’t pronouce it either) has 3 sacks in his last two games . . . Seattle QB Russell Wilson is 10-0 with 22 TDs and 4 INTs at home . . . Player to watch: Titans QB Ryan Fitzpatrick has 72 TDs and 81.5 passer rating since 2010.

Key injuries: TITANS: OUT: LB Zaviar Gooden (hamstring), RB Shonn Greene (knee), QB Jake Locker (hip, knee). QUESTIONABLE: LB Patrick Bailey (hamstring), DT Sammie Hill (ankle), DE Derrick Morgan (shoulder), CB Coty Sensabaugh (concussion), T David Stewart (ankle), CB Blidi Wreh-Wilson (hamstring). PROBABLE: RB Jackie Battle (neck), S Michael Griffin (foot). SEAHAWKS: OUT: T Breno Giacomini (knee), RB Spencer Ware (ankle). DOUBTFUL: LB Bobby Wagner (ankle). QUESTIONABLE: RB Marshawn Lynch (hip), TE Zach Miller (hamstring). PROBABLE: DE Michael Bennett (quadriceps), CB Jeremy Lane (hamstring), WR Sidney Rice (knee), CB Walter Thurmond (knee), C Max Unger (arm).

Arizona at San Francisco

Time: 4:25 p.m. Line: 49ers by 10½.

Records: Cardinals 3-2 (4-1 vs. spread), 49ers 3-2 (3-2 vs. spread).

Comments: Cardinals’ Patrick Peterson has 3 picks in his last two games. He has 12 INTs and 4 punt return TDs since 2011 . . . San Fran DT Tony Jerod-Eddie (hey, he has three first names) collected first career sack last week . . . 49ers WR Anquan Boldin had five 1,000-yard seasons as a Cardinal . . . Since 2007, Arizona’s Larry Fitzgerald has an NFL-high 65 TD catches . . . Player to watch: Niners CB Tramaine Brock had 2 INTs and a return for TD last week.

Key injuries: CARDINALS: QUESTIONABLE: LB Kenny Demens (hamstring), WR Larry Fitzgerald (hamstring). PROBABLE: LB John Abraham (shoulder), LB Jasper Brinkley (groin), G Daryn Colledge (shin), DT Darnell Dockett (groin), S Rashad Johnson (finger), LB Kevin Minter (hamstring), DE Ronald Talley (wrist), LB Daryl Washington (knee). 49ERS: OUT: WR Quinton Patton (foot). QUESTIONABLE: CB Nnamdi Asomugha (knee), G Alex Boone (shoulder), T Anthony Davis (shoulder), C Jonathan Goodwin (illness), DT Ray McDonald (biceps), CB Carlos Rogers (knee), DT Justin Smith (shoulder), LB Patrick Willis (groin). PROBABLE: TE Vernon Davis (hamstring), RB Frank Gore (knee), G Mike Iupati (shoulder), QB Colin Kaepernick (foot), WR Marlon Moore (quadriceps), T Joe Staley (knee), WR Kyle Williams (knee).

Jim McBride can be reached at j_mcbride@globe.com
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