Barry Chin/Globe Staff

The Red Sox hosted the Cleveland Indians Friday night.

Barry Chin/Globe Staff

Cleveland started Justin Masterson in the second game of a weekend series against the Sox.

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A fan missed the chance for a souvenir home run ball hit by the Indians' Carlos Santana (not pictured) in the second inning.

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David Ortiz raced to the plate in an attempt to score from second base.

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The designated hitter was not able to make it in time and was dead at the plate.

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Lackey pitched into the seventh inning.

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He held his glove to his mouth in an effort to stifle a yell after ball four was called, issuing a two-out walk to Yan Gomes (not pictured) in the sixth.

Barry Chin/Globe Staff

A.J. Pierzynski got things going for the Sox with a two-run double.

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Masterson wasn't as sharp as he was in his last start against the Sox in Cleveland.

Barry Chin/Globe Staff

Mike Napoli's opposite-field two-run double in the third inning gave the Red Sox a 5-3 lead.

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Xander Bogaerts and Dustin Pedroia scored on Napoli's double.

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Lackey reacted after the baserunner was ruled safe on a close play at first in the fifth inning.

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He clapped his glove after getting Santana (not pictured) to fly out to right field to end the sixth.

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Lackey has given up three runs or fewer in each of his past five starts, and his 3.24 ERA is the best among Sox starters.

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He was greeted with cheers from the fans and fist bumps from teammates as he left the game.

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Just like old times, but different teams, Indians manager Terry Francona and bench coach Brad Mills stood in the dugout.

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Brock Holt scored the second run on a two-run double by Pedroia (not pictured) in the seventh.

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Pedroia was congratulated at home plate by Daniel Nava as he scored on a single by Ortiz (not pictured).

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Bogaerts connected for a home run in the eighth inning.

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The shortstop looked skyward as he crossed home plate after hitting the homer that ended his 0-for-19 slump.

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Ortiz greeted Bogaerts with a hug in the dugout.

Barry Chin/Globe Staff

Burke Badenhop was pumped up after closing out the game. The Red Sox took a 10-3 win over the Indians.

Barry Chin/Globe Staff

The Sox have won four of their last six games and at 31-36 may yet be able to regain some viability in the division.