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In Peter Farrelly’s 2018 Oscar-winning film, “Green Book,” chauffeur Tony Lip quips: “The world’s full of lonely people afraid to make the first move.”

Neither Farrelly nor his brother, Bobby Farrelly, the director of 1998’s “There’s Something About Mary,” fits that description. Both are being recognized for pressing Hollywood repeatedly and publicly to do a better job of casting and portraying people with disabilities.

The Boston-based Ruderman Family Foundation, a leading voice in calling for more opportunities for the disabled, said Wednesday the brothers are the recipients of its sixth annual Morton E. Ruderman Award in Inclusion.

The foundation said it picked the Farrellys for their outspoken efforts to make movies more inclusive. They’ll be presented with the award next spring.

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“When you tell a story, you want it to take place in a real world — and it’s not a real world if they don’t include everybody,” said Peter Farrelly, who co-wrote and directed “Green Book,” which won Oscars for best picture and best original screenplay.

Bobby Farrelly recalled how the brothers played with children with disabilities in the neighborhood where they grew up in Cumberland, R.I., just over the border from Massachusetts.

“They made us laugh. They were our friends,” he said in a videotaped message.

“And so when we started making movies, we thought, why wouldn’t we include people with disabilities in the movies — in the stories that we tell — because they are a part of our life.”

The brothers have collaborated on other hit films including “Dumb and Dumber,” “Me, Myself & Irene” and “The Heartbreak Kid.”

Ruderman says its research shows that only 5 percent of the characters on top TV shows are played by actors with disabilities. In reality, Peter Farrelly says, 20 percent of the US population has some kind of disability.

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It says Hollywood, meanwhile, frequently depicts people with disabilities in a way that “perpetuates misconceptions and stereotypes.”

The foundation works for more inclusion and opportunities for the disabled. Previous recipients of its award include Olympic swimming champion Michael Phelps, Oscar-winning actress Marlee Matlin and former Democratic US Senator Tom Harkin, an Iowa Democrat who was a driving force behind the Americans With Disabilities Act.