626 confirmed cases, 13 deaths, and 58,254 vaccinations: See today’s new COVID-19 data from Mass.

Senior Boston College nursing student Danielle Palmieri administered the Pfizer-BioNTech COVID-19 vaccine to BC sophomore John Petit inside Boston College's Conte Forum.Jessica Rinaldi/Globe Staff

Massachusetts reported 626 new confirmed coronavirus cases Wednesday, bringing the total number in the state to 654,734.

The Department of Public Health also reported that the high-stakes campaign to vaccinate people got another 58,254 shots into people’s arms.

The department also reported 13 new confirmed coronavirus deaths, bringing the state’s total to 17,357.

The state remains in a struggle with the coronavirus more than a year after it arrived. But thanks to the state’s vaccination campaign, millions are now protected and recent coronavirus numbers have been trending downward.

The DPH said 16,685 people were estimated to have active cases of the potentially deadly virus, and 428 confirmed coronavirus patients were in the hospital.

The DPH also reported that 76,716 more tests had been conducted for coronavirus. The total number of tests administered climbed to more than 22 million.

The DPH reported that the seven-day average rate of positive tests, which is calculated from the total number of tests administered, was at 1.25 percent.

The department said the rate would be 2.14 percent if the effect of college testing programs — in which asymptomatic people can be tested repeatedly in an effort to rapidly identify new cases — is factored out.

The number of new vaccinations brought the total to 6,907,827.

The number of new vaccinations reported Wednesday was greater than on Tuesday, when 56,959 were reported.

The total number of shots administered amounted to 84.1 percent of the 8,215,860 doses shipped to providers in the state so far, the Department of Public Health said.

The total shots administered included 3,857,773 first shots and 2,823,166 second shots of the Moderna and Pfizer two-shot vaccines. It also included 226,888 shots of the Johnson & Johnson one-shot vaccine.

The number of people fully vaccinated — with either two shots of the Moderna or Pfizer vaccines or one shot of the Johnson & Johnson — rose to 3,050,054.

To take a deeper dive into the state’s coronavirus statistics click here.