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London calling not all it’s cracked up to be for Bills, who add more injury to insult of losing

A knee injury in the first quarter left Bills linebacker Matt Milano to be carted away from the action.Peter Nicholls/Getty

The Bills arrived in London jolly. They came out flat. They’re going home battered.

Buffalo rallied but fell short in a 25-20 loss Sunday to the Jaguars at Tottenham Hotspur Stadium.

Starting linebacker Matt Milano left early with a knee injury that is “not looking good,” said coach Sean McDermott. That’s after losing starting cornerback Tre’Davious White a week earlier to a season-ending Achilles tendon injury.

McDermott is not optimistic about DaQuan Jones, either. The defensive end injured a pectoral muscle.

Milano, a first-team All-Pro last season, was hurt in the first quarter while pressuring Jacksonville quarterback Trevor Lawrence. The Boston College product was carted off the field after making three tackles in the game.

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“It’s a knee and lower leg injury,” McDermott said. “I know it’s not looking good right now, but I don’t know any details beyond that at this point.”

Jones “also not looking good at this point,” he added.

Von Miller returned to the Buffalo defense but the NFL’s all-time active sacks leader had little impact, not a surprise given it was his first game in 10 months because of a knee injury.

“Von was on a pitch count today so we didn’t have him through the second half like we would hope down the road,” McDermott said.

Miller said he “got enough reps in to build on … and get ready for the (New York) Giants next week.”

McDermott is definitely not pleased with the scenario of arriving Friday to play a team that had already been in the British capital for a week.

“We’ll see if, whatever comes up down the road in terms of us coming back here, but we need to evaluate everything because I didn’t feel like our energy was good enough early in the game. They had better energy than we did,” McDermott said.

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The Jaguars stayed in town after beating the Atlanta Falcons last week at Wembley Stadium. It’s the first time a team has played consecutive games abroad.

“Our guys were in really good position health-wise. They felt energetic, and they felt good to be here,” Jaguars coach Doug Pederson said. “I did feel like our guys were ready to go. The 10 days over here were good for us.”

Arriving late in the week — as Jacksonville and Atlanta did before their game — is the current trend for teams, who usually cite advice from sports scientists. Teams can choose to come earlier, however, as Baltimore is doing this coming week for its game against Tennessee.

Giants lose QB to neck injury

Daniel Jones walked off the field early in the fourth quarter in Miami Gardens, Fla., knowing his day was over after he had been quickly diagnosed with a neck injury. A few minutes later, his backup Tyrod Taylor was shaken up as well.

Jones had X-rays and said he will undergo imaging tests Monday to determine what’s wrong.

The Giants lost their starting quarterback after he took another beating in their 31-16 loss Sunday to the Dolphins, getting sacked six times and hit plenty of others.

“I don’t know exactly what it is yet,” Jones said. “We’ll know more tomorrow.”

The Giants were already shorthanded against the Dolphins — running back Saquon Barkley’s ankle injury kept him out of a third consecutive game — and have used four starter combinations on the offensive line already.

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The line might be the biggest issue. Jones got beat up early and often; to his credit, he battled, completing 14 of 20 passes for 119 yards with no interceptions. The Giants gave up seven sacks, pushing their total to 30 — tying the second most through five games in NFL history.

Shoulder injury sidelines Colts rookie

The Colts aren’t sure how much time, if any, quarterback Anthony Richardson might miss after leaving in the first half of a 23-16 victory in Indianapolis against the Titans with a right shoulder injury.

Coach Shane Steichen said he didn’t know the extent of the injury immediately following the game. Richardson didn’t speak with reporters and was expected to undergo further evaluation.

The rookie was injured on a 4-yard run with 4:29 left in the first half when he fell awkwardly to the ground with two Tennessee defenders draped around him. Richardson stayed down for several minutes.

It’s the third time this season Richardson has been unable to finish a game he started.

“I think when you have a dynamic player like him, and, obviously, one of his skill sets is as a runner, that’s what makes him really good,” Steichen said. “The designed run that he got hurt on, we ran something similar last week that he popped for a big one, and then, obviously, this week, he got the shoulder on that play. So that’s stuff you’ve got to look at.”

Big scare for Panthers

Panthers guard Chandler Zavala was released from a hospital and traveled home with the team from Detroit after being carted off the field with a neck injury late in the first quarter against the Lions.

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The rookie was injured on a running play and the medical staff took time to secure his neck with a brace. He was placed on a backboard and onto the back of a cart. Zavala was alert and able to move all extremities.

“We think it was a bad stinger, but our medical staff is always going to take every precaution to protect our players,” Panthers coach Frank Reich said after Detroit’s 42-24 win.

Zavala gave a thumbs-up while being carted off the field.