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During the frenzy of construction that has transformed the South Boston Waterfront, there has been no confirmation that a drugstore would show up — until now.

CVS Health spokesman Mike DeAngelis said in an e-mail that the Woonsocket, R.I., company has signed a lease for 11,000 square feet at the intersection of Seaport Boulevard and Boston Wharf Road.

DeAngelis said the company is still finalizing the store’s design. Construction on the store is expected to begin next year, in time for a store opening in late 2016. CVS expects to employ about 20 people there.

The store, he said, will be part of a residential building on what is known as “Block K” of the massive Seaport Square, a project that spans 23 acres that’s being developed by a team led by Boston Global Investors and Morgan Stanley. Newton-based WS Development is the retail developer for the site, DeAngelis said.

The vision for Seaport Square includes a 10-screen movie theater, a Kings bowling center, a fitness center, and apartments, and dozens of retailers and restaurants.

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Skanska USA Commercial Development Inc. and Twining Properties previously bought the Block K site from Seaport Square’s master developer and are constructing a 14-story apartment building there. The Watermark Seaport project will have more than 300 residential units and 25,000 square feet of retail space. The upscale burger chain Shake Shack also has signed a lease for the site.

The CVS chain’s arrival will likely be welcomed by critics who say the South Boston Waterfront’s renaissance has suffered because it lacks the amenities of other neighborhoods, such as a school, drugstore, or full-sized supermarket. The CVS on West Broadway and Rite Aid on East Broadway in South Boston are not within a comfortable walking distance, although CVS operates a two-level store in South Station, on the other side of the Fort Point Channel.

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Jon Chesto can be reached at jon.chesto@globe.com. Follow him on Twitter @jonchesto.