MIT’s new investing Engine raises $200 million

The program, launched in 2016, provides startup founders with money, technical expertise, and access to specialized equipment.

STAT

For Sage Therapeutics, the stakes couldn’t be higher in latest drug study

The Cambridge biotech’s product failed as an epilepsy treatment but may have a future as a drug for postpartum depression.

Johnathan

Millennials are foodies but don’t have pans to prove it, company says

Twentysomething foodies may obsess over their food, but they are generally clueless about cookware, says Made In, a new company that targets millennials.

The Toys “R” Us store in New York’s Times Square in 2015.

Toys ‘R’ Us is said to file for bankruptcy as soon as today

The Chapter 11 reorganization of America’s largest toy chain would deal another blow to brick-and-mortar retail.

Latest Business headlines

Cambridge biotech Disarm raises $30m for drug to slow ALS, other degenerative diseases

The treatment would work to slow or halt the progression of degenerative diseases that affect the nervous system, from ALS to glaucoma.

Toys ‘R’ Us files for Chapter 11 bankruptcy

The bankruptcy filing is the latest blow to brick-and-mortar retail.

PHARMALOT

This CEO promised fair drug pricing, but his latest move is raising anger (and eyebrows)

Allergan’s Brent Saunders made a creative deal to protect patents on a lucrative drug. It’s calling into question his `social contract’ with consumers.

Roche Bros. is going to open in a Waltham apartment building

Wellesley chain is planning a scaled-down version of its regular supermarkets.

Former Fox News contributor says rape allegation blacklisted her

Scottie Nell Hughes claims she was raped by Fox Business Channel anchor Charles Payne.

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An afternoon recap of the day’s most important business news, delivered Monday through Friday.

The Fine Print

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Sean P. Murphy is the Globe’s consumer columnist, and he’s here to take your queries.

Globe Magazine

Special section | Game Changers

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2017/05/11/BostonGlobe.com/Business/Images/gamechangershoriz-6383.jpg 51 bright ideas and breakthroughs for 2017

In a revolutionary place like Boston, innovators and innovations are as common as bad drivers. See who made our annual list.

STAT

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2017/09/18/BostonGlobe.com/National/Images/Mason.jpg In excruciating pain, sickle cell patients are shunted aside

Because of racial bias and inadequate training, patients having painful sickle cell crises often get poor care in emergency rooms.

More Business headlines

Two people familiar with the case say the Google Shopping site is being offered in a bid to appease European Union regulators.

Google said to offer shopping space to rivals

It’s a bid to appease European Union regulators and avoid further antitrust fines, according to two people with knowledge of the case.

Equifax Inc. learned about a major breach of its computer systems in March — almost five months before the date it has publicly disclosed, according to three people familiar with the situation.

Equifax executives’ stock sales said to be focus of criminal probe

Equifax learned about a major breach of its systems in March — five months before the date it has publicly disclosed, according to three people.

Meg O’Leary is leaving the PR firm InkHouse to join a Brooklyn-based startup.

BOLD TYPES

Meg O’Leary cashes out of PR firm to rejoin startup life

O’Leary helped build InkHouse from a small business into one of the region’s biggest PR firms within a decade.

Andrew helped insurers avoid devastating losses from Harvey, Irma

The severity of Andrew, amounting to $25 billion in losses in 2017 dollars, bankrupted 11 insurers.

Martin Luther King Jr. addressed a crowd in 1963. Many Americans mistakenly believe civil rights progress has led to racial economic equality, a Yale professor suggested.

White people are really confident that things are getting better for black people

Americans, especially wealthy whites, vastly overestimate progress toward racial economic equality, according to a new paper by Yale University researchers.

Northrop Grumman to buy Orbital ATK for $7.8b

The military contractor Northrop Grumman is buying Orbital amid a rise in consolidation in the aerospace industry.

Tuesday’s business agenda.

Entrepreneurship panel, agency talks, and other notable events and things to know.

What’s up this week in career-enhancing, learning, and networking

A weekly roundup of events.

John Maraganore, CEO of Alnylam Pharmaceuticals, faces a crucial moment for his company.

STAT

Judgment day nears for Alnylam and a new technology

Soon-to-be released clinicial trial data will reveal much about the Cambridge biotech’s future — as well as RNAi drug development.

Counterculture magazine Rolling Stone to be sold

Jann Wenner started the magazine that would become the counterculture bible for baby boomers in the 1960s.

Alisa Erkes, 28, of Smyrna, Ga., gave up her fight to get a safer painkiller.

Amid opioid crisis, insurers restrict less-addictive but pricier painkillers

Many insurers provide comparatively easy access to generic opioid medications.

Hurricane Irma pulled this house in Vilano Beach, Fla., off a ridge near the ocean — part of the storm’s $50 billion in damage in the state, where proximity to the sea is a big draw.

Post-Irma, Harvard expert urges Florida to rethink economy

Florida’s economy has long thrived on one import above all: people.

Kathie Florsheim very much wanted to keep her Canon printer cartridge out of a landfill but not at the expense of her privacy.

Sean P. Murphy | The Fine Print

Should you have to give up privacy to recycle a printer cartridge?

What Kathie Florsheim learned on Canon’s website stopped her in her tracks.

A Weedmaps billboard on Meridian Street in East Boston.

California marijuana services firm sets up shop in Boston, joins Chamber of Commerce

Weedmaps is the first marijuana-related company to join the Boston-area’s chamber of commerce.

Top row (from left): Heather Campisano, Sherry Lewis DaPonte, Patricia A. Foley, Joseph L. Hooley. Middle row (from left): Kerry Jordan, Martin Kain, Deborah Pullen, Sergeant Gino Provenzano. Bottom row (from left): Maria Santos, Barry Stafford, Henry Vitale.

11 Boston public servants celebrated as ‘unsung heroes’ of community

The annual Henry L. Shattuck Awards recognize unsung leadership and commitment to improving Boston.

Suffolk  Downs.

Boston thinks Suffolk Downs is the key to landing Amazon

Suffolk Downs is emerging as a leading site among city officials as they put together a bid for Amazon.com’s second headquarters.

Screen captures of TV ads for (top, left to right) Lyrica, Eliquis, Xeljanz, Humira, Harvoni, Viagra, Humira, and Latuda.

STAT

Do Americans really watch 16 hours of pharma ads a year?

Can that number possibly be correct? To check, we did the math on the back of the proverbial napkin.

MICHELLE SINGLETARY | THE COLOR OF MONEY

Equifax data breach could have a silver lining

Congress needs to pass legislation allowing consumers to temporarily freeze and unfreeze their own credit files at no charge.

Why companies aren’t in a hurry to fill job openings

Companies say they want to hire. So why aren’t they doing it?

The building housing dozens of businesses, including Black Ink gift shop and Cardullo’s Gourmet Shoppe, are for sale by a family trust.

Harvard Square properties could fetch more than $100 million

A week after the listing for the Brattle Street properties hit the market, more than 100 notices of interest from would-be buyers have come in, brokerage says.

SoFi board says CEO is out immediately amid sexual harassment scandal

SoFi was sued last month by a former employee who argued that sexual misconduct at the company had created a toxic work environment and that he had been fired for reporting sexual harassment to managers.

Fearing anti-semitic speech, Facebook limits audience targeting

Facebook has said it will restrict how advertisers target their audiences on the social network after a report said some were able to seek out self-described “Jew haters.”

Equifax disclosed last week that hackers accessed or stole 143 million Americans’ Social Security numbers, birthdates, and other information.

Key Equifax executives departing after huge data breach

Equifax says its chief information officer and chief security officer are leaving the company.

Boston has more than enough to attract Amazon without extra financial incentives.

Analysis

Dear Amazon, here’s our offer: not one dime

Boston has a lot else to offer, and money shouldn’t matter anyway.

Tracy Palandjian.

FIVE THINGS

Five things you should know about Tracy Palandjian

Palandjian, chief executive at Social Finance Inc., said she was an accidental entrepreneur.

McCall Barrick is a nurse practitioner at the Emerson Center for Weight Loss in Concord.

ON THE JOB

After patients’ weight loss surgery, her work really begins

McCall Barrick helps people before, during and — especially — after a bariatric procedure.

“Our job is to get Amazon excited about Massachusetts,” said Jay Ash, chairman of MassDevelopment’s board.

State agency sets aside $200,000 to help chase Amazon

The Baker administration is getting serious about the quest for the massive company’s second headquarters.

Amazon recently opened a massive distribution center in Fall River.

SCOTT KIRSNER | INNOVATION ECONOMY

Can Amazon deliver what Boston needs?

In seeking to land the company’s headquarters, local leaders must consider whether it will benefit people who already live and work here.

Kate Lauzon, 40, with two of her children. She receives disability payments and works several part-time jobs.

Tourism booms but locals struggle: Behind the two worlds of the Berkshires

The number of people in poverty in Berkshire County rose by nearly a third between 2000 and 2015, even as the number of seasonal home owners increased almost 19 percent.

Friday’s business agenda.

Oktoberfest, tech conference and other notable events and things to know.

Motel 6 workers tipped off immigration agency about guests

Employees at Motel 6 locations in Arizona regularly handed over to the government information that led to its hotel guests being detained and deported, the company has acknowledged.

Eugene Kaspersky is the CEO of Kaspersky Lab. In July, the General Services Administration removed the software maker firm from its list of approved products.

The US case against Kaspersky? It’s secret.

Federal officials have so far declined to release evidence behind their accusations computer firm is a Kremlin stooge.

“It’s a tremendous vote of confidence for someone to place these funds with us,” Boston Foundation president Paul Grogan said.

$50 million donation is Boston Foundation’s biggest ever

The gift comes from the sale of shares in a privately owned Billerica-based educational tech company.

Dow ekes out another record even as other indexes struggle

It was a split decision on Wall Street on Thursday as gains in a handful of industrial and health care companies largely outweighed sluggishness elsewhere in the market, including the technology sector.

Moderna CEO Stéphane Bancel has faced restive investors as progress stalls on some key projects.

Moderna leaves key questions unanswered as investors seek the reality behind the hype

Moderna’s five-hour presentation to investors included cheery updates — but underlined lingering questions about whether it can live up to its own hype.

Sylvia Ferrell-Jones led YA Boston for 10 years.

Illness forces Ferrell-Jones to resign as head of Boston’s YWCA

“It was a difficult decision for all of us. . . . This is the passion of her life, the YW mission,” the chair of YW Boston’s board of directors said.

Sales of beer and wine at the Cambridge store will probably cease in the coming months.

Two-buck chucked in Cambridge: Trader Joe’s to cease alcohol sales at store

Cambridge-area shoppers accustomed to picking up cases of two-buck Chuck from the Trader Joe’s on Memorial Drive may want to stock up now.

Steven Walsh is the new chief executive of the Massachusetts Health & Hospital Association.

Hospital industry group taps ex-lawmaker as new chief

Steve Walsh will head the Massachusetts Health & Hospital Association beginning in November.

The Massachusetts unemployment rate for April will be released Thursday.

Massachusetts jobless rate falls for the first time this year

At 4.2 percent for August, the state is once again below the national average.

epa06203397 Sharon Noeller, resident of the Seabreeze mobile park, surveys the storm surge debris deposited in his backyard after Hurricane Irma struck the Florida Keys in Marathon in the Florida Keys, Florida, USA, 13 September 2017. Many areas remain under a dawn to dusk curfew. EPA/CRISTOBAL HERRERA

CONSUMER ALERT

Do your research before donating to hurricane relief efforts

Know where the money is going, and time your giving to have the greatest benefit.

A new app allows user to follow a beer trail map throughout the state.

One year, 100 breweries. Grand prize: drink with beer legends

Five craft beer fanatics will dine with the founders of Boston Beer, Harpoon, and Night Shift.

Tech Lab by Hiawatha Bray

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Bray writes about technology for the Business section. His Tech Lab column appears on Thursdays.

Shirley Leung

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Leung writes a business column every Wednesday and Friday. Previously she served six years as the business editor overseeing daily and Sunday coverage.