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The cast of a new play about the Boston Marathon bombings has been announced and it includes a few acclaimed Boston actors.

Karen MacDonald and Paula Plum join Amie Lytle, Greg Maraio, Lewis D. Wheeler, Omar Robinson, Ed Hoopman, Katy Sullivan, Sam Tanabe, Danny Bolton, and Tonasia Jones in the cast of “Finish Line: A Documentary Play About the 2013 Boston Marathon,” which will open at the Shubert Theatre March 15. (Tickets are on sale.)

The play, a collaboration between the Boston Theater Company and the Boch Center, is based on interviews with survivors of the 2013 Boston Marathon bombings, as well as runners, doctors, police officers, journalists, clergy, students, and others.

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Many of the actors play multiple parts. MacDonald, for example, will portray Liz Norden, the mother of two sons injured in the blasts, and Paula McLaughlin, the wife of a Boston cop; and Plum will portray TV news anchor Maria Stephanos and Carol Downing, a runner whose family was injured in the bombings.

“As an actor and a native Bostonian, I feel a great responsibility working on ‘Finish Line,’ ” said MacDonald. “I am in awe of these people and am so fortunate to be a part of bringing them to the stage. To lift them up and bear witness to their stories of courage is an honor.”

“Finish Line: A Documentary Play About the 2013 Boston Marathon’’ was co-created by Joey Frangieh and Lisa Rafferty. There were 16 sold-out workshop performances of the play last April, but the production premiering at the Shubert in March has been reconfigured.