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A tractor-trailer overturned Friday on Mystic Valley Parkway near Medford Street in Arlington, spilling gasoline onto the street and closing down the road, police said.

The driver of the truck, a 65-year-old Framingham man, is in serious condition at Beth Israel Deaconess Medical Center, State Police said.

The tractor trailer has been removed from the scene and crews are working to grind down and repave the road, said Captain Richard Flynn of the Arlington Police Department.

The process to clean up the thousands of gallons of fuel is expected to be completed by later tonight and the Mystic Valley Parkway will be reopened between 6 and 8 a.m. on Saturday, he said.


However, Flynn added, quite a bit of gasoline ran into nearby sewers and the Mystic River. That clean-up process has only just begun, and may continue throughout the weekend.

Troopers from the Massachusetts State Police Marine Unit are on scene, assisting the Clean Harbors company in placement and monitoring of hazardous material containment booms in the waterway, State Police said.

A hazmat team from the state fire marshal’s office also responded to the scene, according to Jennifer Mieth, a spokesman for the fire marshal.

The truck involved is owned by JP Noonan Transportation Inc. of West Bridgewater, State Police said. No charges have been filed against the driver at this point.

Todd Feathers can be reached at todd.feathers@globe.com. Follow him on Twitter @ToddFeathers. Haven Orecchio-Egresitz can be reached at haven.egresitz@globe.com.