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A Boston-based Coast Guard cutter seized 4.6 tons of cocaine from vessels in the Panama Canal bound for the United States, officials said.

The Seneca intercepted five vessels carrying $154 million worth of cocaine, said Petty Officer Andrew Barresi, a spokesman for the US Coast Guard in Boston.

Barresi said 15 suspected narcotics traffickers were arrested during the 68 days Seneca was in the eastern Pacific.

This is the third time Seneca has been deployed to that area, Baressi said.

Mina Corpuz can be reached at mina.corpuz@globe.com. Follow her on Twitter @mlcorpuz.