A five-century house tour will be held on Sept. 21 as part of Wayland’s slate of 375th birthday celebrations. The tour will take place from 10 a.m. to 3 p.m. and feature one house from each of the past five centuries. All tours begin at the Wayland Town Center, near the downtown development’s new medical building. Tickets are $25. Because of limited parking at some houses, vans will be used to transport participants. Volunteers are needed. For more information, visit www.wayland375.com.