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COLLEGE PARK, Md. — A federal judge on Friday threw out a lawsuit that challenged Maryland’s newly enacted ban on the sale of dogs and cats by retail pet stores, a statute billed as a check against unlicensed and unsanitary ‘‘puppy mills.’’

Four pet stores, a dog breeder, and a dog broker sued in August to block the law, which took effect Jan. 1. Maryland was the second state after California to pass such restrictions.

The law bans pet stores from selling dogs and cats but encourages them to collaborate with animal welfare groups to “showcase” dogs from shelters, animal control units, and “local breeders.”

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US District Judge Ellen Hollander, who also denied the plaintiffs’ request for a preliminary injunction blocking the law’s enforcement, said she found ample evidence that state lawmakers had a ‘‘rational basis’’ for enacting the statute.

“Protecting consumers, reducing financial support for mill breeders, and encouraging pet adoption are indisputably legitimate state interests,” she wrote in her 79-page decision.

Hollander said the plaintiffs essentially argued that lawmakers improperly tried to harm pet stores by siding with animal rights groups.

“This argument is without merit. Siding with one group does not necessarily signify hostility towards another,” the judge wrote.

The pet stores have said the ban will put them out of business. One of the plaintiffs, Just Puppies, closed “for a period” after the law took effect last month, said plaintiffs’ attorney Jonathan Kagan. The ban has already “significantly impacted” the stores that have stayed open in hopes of getting a favorable court ruling, he added.

Kagan couldn’t immediately say if his clients would appeal the ruling. “We’re still trying to digest it,” he said.

The pet stores argued the ban is unconstitutional, violating the commerce and equal protection clauses of the 14th Amendment. Their suit said the legislation’s intent to facilitate sales from local breeders discriminates against out-of-state breeders and brokers.

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The lawsuit also said animal welfare organizations have made unfounded claims that pet stores are fueling the growth of puppy mills. The suit claimed the ban effectively shifts the sale of puppies from regulated retailers to unregulated sources, such as sellers placing ads on the Internet or in newspapers.

The judge said there are “certainly grounds to support plaintiffs’ belief that, in effect, the cure is worse than the disease.’’

“But, whatever the Act’s soundness, that is a judgment committed to the Legislature,” Hollander added.

The first law of this kind took effect in January 2019 in California. Unlike Maryland’s blanket ban on the sale of dogs and cats by pet stores, California law prohibits pet stores from selling a dog, cat, or rabbit unless it came from an animal shelter or rescue group.

Maine also recently enacted a law prohibiting the sale of cats and dogs in stores, and New York is contemplating a pet store ban similar to Maryland’s, Hollander noted.