Time: 1 p.m. Line: Colts by 5½.
Records: Titans 4-8 (4-8 vs. spread), Colts 8-4 (8-4 vs. spread).
Comments: Colts beat Titans, 19-13, in overtime Oct. 28 . . . Indianapolis has won 15 of last 19 in the series . . . Tennessee’s Chris Johnson averages 103.3 yards from scrimmage vs. Indianapolis and is just 7 yards shy of his fifth straight 1,000-yard season . . . Colts’ Andrew Luck’s eight wins are most for a rookie quarterback drafted No. 1 overall in Super Bowl era . . . Indianapolis LB Jerrell Freeman has a team-high 107 tackles . . . Player to watch: Tennessee QB Jake Locker posted his second career 300-yard passing game last week.
Injuries: TITANS: OUT: LB Colin McCarthy (concussion), WR Damian Williams (hamstring). QUESTIONABLE: WR Lavelle Hawkins (ankle), T Michael Roos (knee), DE Kamerion Wimbley (toe). COLTS: OUT: RB Donald Brown (ankle), G Joe Reitz (head), S Tom Zbikowski (knee). QUESTIONABLE: T Winston Justice (head).
Time: 1 p.m. Line: Bears by 3.
Records: Bears 8-4 (6-6 vs. spread), Vikings 6-6 (4-7-1 vs. spread).
Comments: Bears hammered Vikings, 28-10, Nov. 25 . . . Chicago’s Matt Forte is 37 scrimmage yards shy of his fifth straight 1,000-yard season . . . Minnesota’s Adrian Peterson has rushed for 947 yards and 6 TDs in his last six games . . . Vikings TE Kyle Rudolph has caught a TD pass in three straight . . . Chicago’s Henry Melton leads NFC defensive tackles with 6 sacks . . . Minny QB Christian Ponder is 4-1 in his last five home starts . . . Player to watch: Chicago QB Jay “Cranky Pants” Cutler is 5-0 with 13 TDs in his last five vs. Vikings.
Key injuries: BEARS: OUT: WR Earl Bennett (concussion), CB Tim Jennings (shoulder), LB Brian Urlacher (hamstring). QUESTIONABLE: RB Michael Bush (ribs), DT Stephen Paea (foot), G Chris Spencer (knee). VIKINGS: PROBABLE: DE Jared Allen (shoulder, back), LB Jasper Brinkley (shoulder).
Time: 1 p.m. Line: Redskins by 2½.
Records: Ravens 9-3 (5-6-1 vs. spread), Redskins 6-6 (7-5 vs. spread).
Comments: Why does this game make me think of interleague play? . . . Redskins rookie Robert Griffin III is 46 of 63 for 667 yards and 9 TDs in his last three games . . . Ravens safety Ed Reed has an NFL-best 61 INTs since joining the NFL in 2002 . . . Washington’s Alfred Morris leads all rookies with 1,106 rushing yards . . . Baltimore’s Ray Rice has 11 total TDs in 17 games vs. NFC foes . . . Ravens are 9-1 when Torrey Smith catches at least one TD pass . . . Player to watch: Redskins LB Ryan Kerrigan is only NFLer with 10-plus sacks and 2 INT TDs.
Key injuries: RAVENS: OUT: TE Ed Dickson (knee), LB Dannell Ellerbe (ankle). DOUBTFUL: CB Jimmy Smith (abdomen). QUESTIONABLE: CB Asa Jackson (shoulder), CB Chris Johnson (thigh), LB Terrell Suggs (biceps). REDSKINS: QUESTIONABLE: LB London Fletcher (ankle), CB DeAngelo Hall (ankle, knee), T Trent Williams (thigh).
Time: 4:25 p.m., Fox Line: Giants by 5.
Records: Saints 5-7 (6-6 vs. spread), Giants 7-5 (5-6-1 vs. spread).
Comments: The Giants are on TV again — shocker! . . . Jints lead series, 14-12 . . . Nawlins QB Drew Brees is 4-0 vs. New York with 11 TDs, zero INTs, and 122.1 passer rating . . . Giants QB Elite Manning has completed 176 of 279 for 2,316 yards and 17 TDs in his last eight home games . . . Since 2010, Saints’ Jimmy Graham leads NFC TEs with 27 TDs . . . New Orleans DE Cameron Jordan has a team-high 7 sacks . . . Player to watch: New York’s Hakeem Nicks has 12 catches for 201 yards and TD in two career games vs. Saints.
Key injuries: SAINTS: OUT: T Charles Brown (knee), CB Corey White (knee). CB Johnny Patrick (illness), WR Courtney Roby (hamstring), T Zach Strief (groin), TE David Thomas (knee), DE Martez Wilson (toe). GIANTS: OUT: TE Travis Beckum (knee), S Tyler Sash (hamstring). DOUBTFUL: S Kenny Phillips (knee). QUESTIONABLE: WR Hakeem Nicks (knee).
Time: 1 p.m. Line: Bills by 3.
Records: Rams 5-6-1 (8-4 vs. spread), Bills 5-7 (6-6 vs. spread).
Comments: Rams haven’t visited Orchard Park, N.Y., since 2004 (lucky buggers!) . . . Buffalo QB Ryan Fitzpatrick (a Rams draft pick in 2005) is 2 TD passes shy of passing Jack Kemp (77) for third most in team annals . . . Rookie Rams WR Chris Givens collected 11 catches last week . . . Bills lead AFC at 147.9 yards rushing per game . . . Player to watch: Bills DE Mario Williams has 5 sacks in last three games.
Key injuries: RAMS: OUT: TE Mike McNeill (thigh). QUESTIONABLE: WR Danny Amendola (foot), LB Mario Haggan (elbow). PROBABLE: RB Steven Jackson (foot), C Scott Wells (knee). BILLS: OUT: DE Mark Anderson (knee), C Eric Wood (knee). QUESTIONABLE: DT Spencer Johnson (ankle), WR Stevie Johnson (hamstring), CB Leodis McKelvin (back), CB Justin Rogers (foot), LB Chris White (back), CB Aaron Williams (knee).
Time: 1 p.m., Fox Line: Bengals by 3.
Records: Cowboys 6-6 (4-8 vs. spread), Bengals 7-5 (6-5-1 vs. spread).
Comments: Bengals are shooting for their second straight season with a five-game winning streak . . . The Cowboys have won three of last four . . . Cincy QB Andy Dalton has thrown 7 TD passes and zero INTs in last two home games . . . Tony Romo needs one TD pass to become first Dallas QB with 20 in five seasons . . . Player to watch: Bengals’ BenJarvus Green-Ellis is 115 rushing yards shy of his second 1,000-yard season.
Key injuries: COWBOYS: OUT: S Charlie Peprah (foot), NT Jay Ratliff (groin), CB Orlando Scandrick (hand). PROBABLE: WR Miles Austin (hip), C Ryan Cook (knee), RB Felix Jones (knee), DT Sean Lissemore (ankle), G Nate Livings (ankle), RB DeMarco Murray (foot), T Tyron Smith (ankle), LB Anthony Spencer (calf), RB Lawrence Vickers (knee). BENGALS: OUT: CB Dre Kirkpatrick (head). DOUBTFUL: K Mike Nugent (calf), RB Cedric Peerman (ankle).
Time: 1 p.m. Line: Browns by 7.
Records: Chiefs 2-10 (5-7 vs. spread), Browns 4-8 (7-4-1 vs. spread).
Comments: Chiefs RB Peyton Hillis scored his first TD of the season last week. He spent last two seasons in Cleveland, where he didn’t make a lot of friends . . . Browns rookie RB Trent Richardson averaging 98.5 yards per game in last five . . . KC coach Romeo Crennel used to be the Browns coach . . . Player to watch: Cleveland’s Josh Gordon leads all rookies with 646 receiving yards.
Key injuries: CHIEFS: DOUBTFUL: S Abram Elam (quadriceps). QUESTIONABLE: T Branden Albert (back), G Jeff Allen (illness), S Eric Berry (hand, illness), CB Brandon Flowers (hamstring), G Russ Hochstein (back), LB Derrick Johnson (hamstring), S Kendrick Lewis (shoulder). PROBABLE: LB Tamba Hali (knee), G Ryan Lilja (knee). BROWNS: PROBABLE: WR Travis Benjamin (finger), TE Jordan Cameron (groin), WR Joshua Cribbs (shoulder, chest), LB James-Michael Johnson (finger), T Ryan Miller (forearm).
Time: 1 p.m. Line: Buccaneers by 7½.
Records: Eagles 3-9 (2-9-1 vs. spread), Buccaneers 6-6 (8-2-2 vs. spread).
Comments: Eagles’ Bryce Brown last week became first RB to rush for 150-plus yards in his first two career starts since Gary Brown (no relation) in 1970 . . . Tampa Bay’s Josh Freeman has thrown 18 TD passes in last eight games . . . LB DeMeco Ryans leads Eagles with 91 tackles . . . Bucs have NFL’s best run defense (82.3) and worst pass defense (309.4) . . . Player to watch: Eagles QB Nick Foles has thrown for 793 yards in four games.
Key injuries: EAGLES: OUT: S Kurt Coleman (chest), RB LeSean McCoy (concussion), T Nate Menkin (throat), DT Mike Patterson (illness), QB Michael Vick (concussion). QUESTIONABLE: RB Chris Polk (toe). BUCCANEERS: OUT: CB LeQuan Lewis (knee). QUESTIONABLE: DT Roy Miller (head).
Time: 1 p.m. Line: Falcons by 3½.
Records: Falcons 11-1 (7-4-1 vs. spread), Panthers 3-9 (5-7 vs. spread).
Comments: Falcons beat Panthers, 30-28, in OT Sept. 30 . . . Atlanta QB Matt Ryan has thrown for 1,088 yards and 10 TDs in last four vs. Carolina (all wins) . . . Panthers QB Cam Newton only player in history with at least 30 passing TDs and 20 rushing TDs in first two seasons . . . Falcons had 5 picks last week . . . LB Luke Kuechly leads Panthers with 115 tackles . . . Player to watch: Falcons WR Roddy White had 8 catches for 169 yards and 2 TDs in September win over Panthers.
Key injuries: FALCONS: QUESTIONABLE: DT Peria Jerry (quadriceps), S William Moore (hamstring), CB Asante Samuel (shoulder), RB Michael Turner (elbow). PANTHERS: DOUBTFUL: RB Jonathan Stewart (ankle). QUESTIONABLE: LB James Anderson (back, eye), G Jeff Byers (back), DT Dwan Edwards (wrist), S Charles Godfrey (back), WR Brandon LaFell (toe). PROBABLE: TE Greg Olsen (back).
Time: 1 p.m. Line: Jets by 3.
Records: Jets 5-7 (6-6 vs. spread), Jaguars 2-10 (6-6 vs. spread).
Comments: Jets QB Mark Sanchez back in the saddle after being benched last week . . . Safe bet the crowd will be calling for hometown boy Tim Tebow all game . . . Jaguars are 3-0 at home vs. Jets . . . David Harris (91 tackles) leads a New York defense that held Arizona to 137 total net yards last week . . . Player to watch: Jacksonville QB Chad Henne was 3-1 all-time vs. Jets when he was Dolphins QB.
Key injuries: JETS: OUT: WR Clyde Gates (concussion). DOUBTFUL: DT Damon Harrison (ankle), TE Dustin Keller (ankle). QUESTIONABLE: WR Stephen Hill (knee), DT Sione Po’uha (low back), QB Tim Tebow (ribs). JAGUARS: OUT: G Mike Brewster (hand), RB Rashad Jennings (concussion), RB Maurice Jones-Drew (foot), CB Aaron Ross (calf), DE George Selvie (concussion), WR Cecil Shorts (concussion).
Time: 1 p.m., CBS Line: Steelers by 8.
Records: Chargers 4-8 (5-7 vs. spread), Steelers 7-5 (5-6-1 vs. spread).
Comments: Chargers are 18-4 in December under Norv Turner (I know, I know, call Ripleys!) . . . Pittsburgh is 14-0 vs. San Diego in the regular season . . . Steelers QB Big Ben Roethlisberger is 134 passing yards shy of becoming 25th NFLer to reach 29,000 . . . San Diego LB Shaun Phillips has 2½ sacks and a forced fumble in four games vs. Pittsburgh . . . Player to watch: Steelers’ Shaun Suisham is 24 of 25 on field goals this season, with three game-winners.
Key injuries: CHARGERS: OUT: LB Donald Butler (groin), T Jeromey Clary (knee), WR Eddie Royal (hamstring). DOUBTFUL: G Tyronne Green (hamstring). QUESTIONABLE: T Mike Harris (ankle). PROBABLE: LB Jarret Johnson (back), S Corey Lynch (quadriceps), TE Dante Rosario (hamstring), S Darrell Stuckey (hamstring). STEELERS: OUT: T Mike Adams (ankle), CB Ike Taylor (ankle), LB LaMarr Woodley (ankle). QUESTIONABLE: QB Byron Leftwich (ribs). PROBABLE: WR Antonio Brown (ankle), P Drew Butler (illness), S Ryan Clark (hip), G Willie Colon (knee), WR Jerricho Cotchery (ribs), RB Will Johnson (concussion), S Troy Polamalu (not injury related), QB Ben Roethlisberger (right shoulder), WR Emmanuel Sanders (shoulder), WR Mike Wallace (knee).
Time: 4:05 p.m. Line: 49ers by 10½.
Records: Dolphins 5-7 (6-6 vs. spread), 49ers 8-3-1 (7-5 vs. spread).
Comments: Miami TB Reggie Bush averaging 116.6 rushing yards in December the last two seasons . . . San Francisco QB Colin Kaepernick has a 100.1 passer rating in three starts . . . 49ers defense allowing an NFL-low 14.3 points per game . . . Dolphins QB Ryan Tannehill’s 2,559 passing yards are a rookie franchise record (yes, even more than Don Strock) . . . Player to watch: San Fran LB NaVorro Bowman has a team-high 105 tackles.
Key injuries: DOLPHINS: QUESTIONABLE: S Jimmy Wilson (hip). PROBABLE: TE Charles Clay (ribs), LB Karlos Dansby (biceps), TE Anthony Fasano (hip), P Brandon Fields (left knee, right knee), RB Jorvorskie Lane (knee), LB Koa Misi (finger), LB Austin Spitler (ankle). 49ERS: DOUBTFUL: WR Mario Manningham (shoulder). PROBABLE: K David Akers (pelvis), LB NaVorro Bowman (shoulder), CB Tarell Brown (hamstring), CB Chris Culliver (illness), LB Tavares Gooden (knee, elbow), RB Frank Gore (wrist), G Mike Iupati (shoulder), CB Carlos Rogers (knee), LB Aldon Smith (shoulder), LB Patrick Willis (shoulder).
Time: 4:25 p.m. Line: Seahawks by 10.
Records: Cardinals 4-8 (5-6-1 vs. spread), Seahawks 7-5 (8-4 vs. spread).
Comments: Cardinals beat Seahawks, 20-16, in Week 1 . . . Arizona is on an eight-game losing streak . . . Seattle rookie QB Russell Wilson is 5-0 at home with 11 TDs and zero INTs . . . Cardinals DE Calais Campbell has 5 sacks in his last three games in Emerald City . . . Seahawks’ Marshawn Lynch has rushed for 100-plus yards in four of last six . . . Player to watch: Arizona’s Larry Fitzgerald has 106 career receptions vs. Seattle.
Key injuries: CARDINALS: DOUBTFUL: DE Ronald Talley (ankle). QUESTIONABLE: DE Calais Campbell (calf), QB Kevin Kolb (ribs), WR Andre Roberts (ankle), RB Beanie Wells (knee). SEAHAWKS: OUT: CB Marcus Trufant (hamstring). QUESTIONABLE: LB Leroy Hill (ankle).
Time: 8:20 p.m., NBC Line: Packers by 6½.
Records: Lions 4-8 (5-7 vs. spread), Packers 8-4 (6-6 vs. spread).
Comments: Packers beat Lions, 24-20, Nov. 18 . . . Cheeseheads lead series, 92-65-7, and have won 24 of last 27 . . . Last time the teams met at Lambeau Field, Lions QB Matthew Stafford threw for 520 yards and 5 TDs in a 45-41 loss in which Packers backup Matt Flynn threw 6 TDs . . . Green Bay WR Greg Jennings (love those Old Spice commercials) has a TD in two of last three vs. Lions . . . Player to watch: Detroit’s Calvin Johnson is first NFLer in history with four straight 140-plus yard receiving games.
Key injuries: LIONS: QUESTIONABLE: T Jeff Backus (hamstring), S Louis Delmas (knee), DT Nick Fairley (quadriceps), CB Chris Houston (ankle), CB Jacob Lacey (foot, Achilles), DT Corey Williams (knee). PACKERS: OUT: LB Clay Matthews (hamstring), WR Jordy Nelson (hamstring), RB James Starks (knee), DE C.J. Wilson (knee), S Charles Woodson (collarbone). DOUBTFUL: DE Mike Neal (shoulder). QUESTIONABLE: G T.J. Lang (ankle), LB Terrell Manning (shoulder). PROBABLE: WR Donald Driver (thumb), C Jeff Saturday (foot), CB Sam Shields (ankle).Jim McBride can be reached at email@example.com.