■ Can Mansfield stop Everett?
Spearheaded by junior linebackers Vinnie Holmes and Nick Marciano, the host Hornets are talented, and stout defensively. But Everett, under first-year coach Theluxon Pierre, is still an offensive juggernaut. Will star corner Khristian Conner be able to contain Virginia Tech-bound senior Mike Sainristil on the outside? Pick: EVERETT
■ Bounce back for X-men or B-R?
Xaverian and Bridgewater-Raynham suffered decisive losses in its openers. These hard-nosed teams meet at B-R Friday night in a rivalry that picked up intensity when the Trojans snapped the Hawks’ 25-game winning streak two years ago. Pick: XAVERIAN
■ More firepower for CM?
New Catholic Memorial coach John DiBiaso had his Knights firing on all cylinders during a 49-25 win over host St. John’s Shrewsbury. Will CM continue to light it up in a potential shootout against Stoughton at Stonehill College? Pick: CATHOLIC MEMORIAL
■ Sizing up Hopkinton
Needham is led by 6-foot-5-inch tight end Matt Smith, a Duke commit and one of the best targets in the state. Can the Hillers match up with Smith on the interior and speedster Odahri Hibberts on the outside? Pick: HOPKINTON
■ Melrose experienced enough?
Defending Division 4 champion Melrose has won 13 straight home games, but returns only one offensive starter. Coming off a 35-7 drubbing of Springfield Central in which tailback James Dillon scored all five touchdowns, Lincoln-Sudbury represents a very stiff challenge. Pick: LINCOLN-SUDBURY
■ South Shore quarterback duel
Duxbury’s John Roberts accounted for six total touchdowns in a 40-14 win over Bridgewater-Raynham, and Scituate’s Aidan Sullivan tallied three in a 34-14 win over Norwell in Week 1. Who is the Patriot League king? Pick: DUXBURY
■ Return of the Boxers?
Brockton put on a resounding performance in a 42-14 win over Lexington. Will the Boxers continue to put last year’s 3-8 season in the rearview with a tough win at Natick? Pick: BROCKTON
■ Best west of 495?
Despite their respective losses to Catholic Memorial and Lincoln-Sudbury, St. John’s Shrewsbury and Springfield Central remain the favorites to represent West/Central in the Division 3 Super Bowl. The two clash Friday at Berte Field in Springfield in what could be a preview of the D3 state semifinals. Pick: ST. JOHN’S
■ Division 1 tamers?
Tewksbury handled D1 program Lawrence, 34-6, in its home opener and will now go on the road against another D1 team in Methuen. Redmen coach Brian Aylward should have enough tricks up his sleeve to earn a 2-0 start.
■ City League contenders?
Tech Boston and the new Boston English/New Mission co-op are poised to make some noise. The Bears dropped a stunner to Georgetown in Week 1 and English/New Mission defeated Keefe Tech, 36-34, behind 159 rushing yards from Takari Hobbs. Pick: TECHBOSTON
Nate WeitzerNate Weitzer can be reached at email@example.com.