Genetic tests for psychiatric drugs spur hope, doubts

New tests that identify the best drugs based on a patient’s DNA have limited science behind them and many questions ahead.

US Congressman Patrick Kennedy (left) and his father, US Senator Edward Kennedy in Pawtucket, R.I. in 2006.

Patrick Kennedy reveals struggles with his father

Kennedy’s new book, scheduled to be released Monday, provides an intimate picture of a dysfunctional family.

Bernie Sanders addressed a near-capacity crowd of 20,000 at the Boston Convention and Exhibition Center.

Keith Bedford/Globe Staff

Sanders draws big crowds in Mass. campaign swing

Bernie Sanders addressed a near-capacity crowd of 20,000 in Boston, with a few thousand more in an overflow room.

Afghan surgeons work in an undamaged part of the MSF hospital in Kunduz after the operating rooms were destroyed in an air strike.

Airstrike’s toll in Afghanistan sparks outrage

At least 19 were killed after a Doctors Without Borders hospital was hit by what appears to have been a US airstrike.

Technology updates pipe organs, but not without controversy

The passionate and proudly obscure world of organ building is torn over the revolutionary digital organ created by a Needham company.

A sign in remembrance of those killed at Umpqua Community College was displayed at a local business in Roseburg, Ore.

Oregon shooter killed himself, sheriff says

The shooter in Roseburg, Ore., killed himself as deputies arrived, Sheriff John Hanlin said.

// Neighborhood activists unite to protest crisis in housing

Hundreds gathered in Dorchester as corporate landlords, they said, displace the poor and traditional communities of color.

From top, Joseph Amoroso, Bella’s biological father; Rachelle Bond; and her boyfriend, Michael McCarthy.

Before she was Baby Doe

Bella Bond was in many ways a typical toddler. But her young life was hanging by a thread.

Tobias Vanderhoop heads the Aquinnah Wampanoag.

Martha’s Vineyard casino proposal splits island

The Aquinnah Wampanoag tribe says it needs the revenue from a casino on Martha’s Vineyard, but others say it would be out of place.

A look at the production floor at John Matouk & Co. in Fall River, maker of bed and bath linens.

For state’s Gateway Cities, a long-awaited rebound

Sky-high unemployment rates are falling as the benefits of a six-year expansion finally reach these struggling communities, known as Gateway Cities.

Rabbi Liza Stern (center) gaves students at Congregation Eitz Chayim a lesson in honey extraction and a sampling of the sweet honey.

Cambridge synagogue pledges to open arms to refugees

For members of Eitz Chayim Congregation, the scenes of refugees’ desperation struck a chord.

Under cloudy skies, Navin Mangalee rode Liberty St. Outlaw to first, in front of Guillermo Rodriguez on Nuestra Senior winning by a horse length in the third race of the day.

Barry Chin/Globe Staff

Second ‘race festival’ at Suffolk Downs draws 8,544

Despite the cold weather and a howling wind Saturday, racing went off without a hitch.

Tourists watched as waves battered the beach in Ocean City, Md., on Saturday. Hurricane Joaquin could produce high surf and rip currents throughout the East Coast, forecasters said

Four sailors from Maine said to be on missing cargo ship

A cargo ship with 33 people aboard was missing as Hurricane Joaquin moved out to sea, but the threat of strong waves remained, forecasters said.

Red Sox interim skipper Torey Lovullo could be in demand for managerial openings.


Red Sox in awkward spot with John Farrell, Torey Lovullo

Lovullo will be a managerial commodity, but the Red Sox might want to keep him in case Farrell can’t return.

BOSTON, MA - JULY 5: Hanley Ramirez #13 of the Boston Red Sox celebrates with teammates Pablo Sandoval #48 and David Ortiz #34 after hitting a two-run home run during the seventh inning against the Houston Astros at Fenway Park on July 5, 2015 in Boston, Massachusetts. (Photo by Rich Gagnon/Getty Images)

Nick Cafardo/On Baseball

Red Sox’ big-money players have to earn keep in 2016

With trades unlikely, Hanley Ramirez and Pablo Sandoval top the list of underperforming players who need to rebound.

// This man ‘owned’ — for 1 minute

Google is worth more than $400 billion. For a minute this week, Sanmay Ved thought he had improbably acquired its domain — for $12.

The Big Picture

Pat Greenhouse/Globe Staff

Globe photos of the month

Here’s a look at some of the best images taken by Globe photographers in September.


BetaBoston | Innovation Economy

//[1]-4929--90x90.jpg Insight is failure’s silver lining

Failure is an enormously powerful learning experience for entrepreneurs — yet most are happy to leave it behind them, undiscussed.


// Vatican distances pope from Kentucky clerk Kim Davis

The Vatican said the pontiff did not intend the encounter as a form of support for her case.